Recombinant Mouse Antibody (3E2) is capable of binding to Staphylococcal enterotoxin B (SEB) , expressed in Chinese Hamster Ovary cells (CHO). This is a neutralizing mAb that recognizes SEB with high specificity and sub-nanomolar affinity. It strongly inhibits SEB-induced T cell proliferation and activation.
Figure 1 Fluorescence photomicrographs showing the effects of various fusion proteins and monoclonal antibody controls.
(A) Representative image of C. parvum sporozoites after a 30-min exposure to either PBS, the CHO cell supernatant, 4H9-G1, 4H9-G2b, the 18.44 MAb, 4H9-G1- PLA2, 3E2-G1, or the 3E2 MAb. (B) Representative image of C. parvum sporozoites after a 30-min exposure to either 4H9-G2b-LL37, 4H9-G1- LL37, 3E2-G1-LL37, 3E2-Mhalf-LL37, or 3E2-Mmono-LL37. (C) C. parvum sporozoites after exposure to 18.44-G1-PLA2 for 30 min. (D) Heatkilled sporozoites. Viability or cell death was determined by the addition of fluorescein diacetate (green) (live cells) and propidium iodide (red) (dead cells). Each component was used at 25 ug/ml.
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