Anti-Human TCR Recombinant Antibody (BMA 031)
CAT#: TAB-545CT
Recombinant monoclonal antibody specifically binds to the human alpha/beta TCR. This antibody can be potentially used in treating T-cell malignancies.
Published Data
FC
Figure 1 Expression of TCR on wild-type Jurkat (JK-WT).
Flow cytometric analysis of the surface expression of TCR/CD3 complex. BMA031 is a pan-TCR αβ antibody.
Chung, S., & Strominger, J. L. (1995). Regulation of T-cell antigen receptor (TCR) alpha-chain expression by TCR beta-chain transcripts. Proceedings of the National Academy of Sciences, 92(9), 3712-3716.
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Specifications
- Host Species
- Humanized
- Type
- Humanized antibody
- Antibody Isotype
- IgG1
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- BMA 031
- Applications
- FC
- Related Disease
- Autoimmune Disease, T-cell malignancies
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry.
Target
- Alternative Names
- TCR; T cell receptor; TCRA; TCRB
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Customer Review
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Excellent for Flow Cytometry
I used the Anti-TCR Antibody for flow cytometry, and it worked great! It helped me identify T cells in my samples easily. The staining was clear and bright, and I could see the different T-cell populations. It was simple to use, and the results were consistent every time. This antibody has become an important part of my research on the immune system.
Useful in Immune Research
This antibody has been very useful in our immune system research. It helps us study how T cells work and interact with other cells. It's a valuable resource that has contributed to important findings in our projects.
Great Customer Service
The customer service team was friendly and helpful when I had inquiries. They provided the information I needed promptly. Good customer service enhances the overall experience with this product.
Q&As
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Can this antibody be used in flow cytometry?
A: Yes, the Anti-TCR Therapeutic Antibody is suitable for flow cytometry applications. It can bind to T-cell receptors on live or fixed cells, allowing researchers to identify and analyze different T-cell populations based on TCR expression. This is helpful for studying immune cell distributions and functions in research studies.
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Can this antibody be used to study autoimmune diseases?
A: Yes, researchers can use this antibody to study autoimmune conditions in experimental models. By targeting the T-cell receptor, it helps investigate how T cells contribute to autoimmune reactions. This can provide insights into disease mechanisms and aid in the development of new research strategies for autoimmune diseases.
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Can this antibody help in cancer immunology research?
A: Yes, this antibody is valuable in cancer immunology studies. By targeting T-cell receptors, it allows researchers to explore how T cells recognize and respond to cancer cells. This can provide insights into immune surveillance mechanisms and contribute to the development of immunotherapy research strategies.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-545CT, RRID: AB_3111971)
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Related Diseases
Asthma
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Amyotrophic Lateral Sclerosis
Maturity Onset Diabetes of the Young
Related Signaling Pathways
TCR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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