Anti-Human TCR Recombinant Antibody (WT31) (CAT#: TAB-549CT)

Recombinant monoclonal antibody specifically binds to human TCR alpha/beta. This antibody can be potentially used in treating T-cell malignancies.


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Inhib

Figure 1 Inhibition of tetramer-binding to T cells by preincubation with anti-CD3 and anti-TCR antibodies.

Figure 1 Inhibition of tetramer-binding to T cells by preincubation with anti-CD3 and anti-TCR antibodies.

CTL INFA24 was preincubated with 3-fold increasingconcentrations ranging from 0.07–50 μg/ml of anti-CD3 antibodies, SPV-T3b (○), OKT3 (■), and anti-TCR antibodies WT31 (△) and T10B9 (●) or control IgG (X), followedby incubations with GAM-Ig and HLA-A2/flu tetramer. Left panel: binding intensity (MFI) of anti-CD3 or anti-TCR antibodies or control IgG to CTLINFA24 T cells.

Weder, P., Schumacher, T. N., Spits, H., & Luiten, R. M. (2012). Testing for HLA/peptide tetramer-binding to the T cell receptor complex on human T lymphocytes. Results in immunology, 2, 88-96.


Specifications

  • Host Species
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • WT31
  • Applications
  • Inhib
  • Related Disease
  • Autoimmune Disease, T-cell malignancies

Applications

  • Application Notes
  • This antibody has been reported for use in Inhibition assay.

Target

  • Alternative Names
  • TCR; T cell receptor; TCRA; TCRB

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

Mouse Antibody

CAT Product Name Application Type
TAB-595CL Mouse Anti-TCR Recombinant Antibody (TAB-595CL) FuncS Mouse IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-248 Afuco™ Anti-TCR ADCC Recombinant Antibody (Maslimomab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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