Anti-Human TCR Recombinant Antibody (KJ1-26)
CAT#: TAB-559CT
Recombinant monoclonal antibody specifically binds to DO-11.10 T-cell receptor. This antibody can be potentially used in treating T-cell malignancies.
Published Data
FC
Figure 1 Gating of OVA-specific CD4⁺ T cells.
Dead cells were excluded by FVS450 staining. OVA-specific CD4⁺ T cells were gated as CD4⁺ KJ1-26⁺ among live cells.
Ding, Z., Dahlin, J. S., Xu, H., & Heyman, B. (2016). IgE-mediated enhancement of CD4+ T cell responses requires antigen presentation by CD8α− conventional dendritic cells. Scientific reports, 6, 28290.
IF
Figure 2 The other half of each spleen was frozen and spleen sections were stained and analysed by confocal microscopy.
DO11.10 TCR (clone KJ1-26) mAb, red. Images show T cell areas (640 μm × 640 μm) representative of 6 T cell zones from 2 non-consecutive sections per sample in each group. Scale bar represents 100 μm.
Ding, Z., Dahlin, J. S., Xu, H., & Heyman, B. (2016). IgE-mediated enhancement of CD4+ T cell responses requires antigen presentation by CD8α− conventional dendritic cells. Scientific reports, 6, 28290.
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Specifications
- Host Species
- Humanized
- Type
- Humanized antibody
- Antibody Isotype
- IgG1
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- KJ1-26
- Applications
- FC, IF
- Related Disease
- Autoimmune Disease, T-cell malignancies
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Immunofluorescence.
Target
- Alternative Names
- TCR; T cell receptor; TCRA; TCRB
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Related Diseases
Asthma
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Amyotrophic Lateral Sclerosis
Maturity Onset Diabetes of the Young
Related Signaling Pathways
TCR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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