Mouse Anti-TF Recombinant Antibody (clone 6A6) (CAT#: PABL-343)
Recombinant Mouse Antibody (6A6) is capable of binding to TF, expressed in Chinese Hamster Ovary cells (CHO). This antibody is able to completely neutralize the anticoagulant activity of D3H44 in tissue factor-dependent functional assays, such as endotoxin-induced whole blood clotting, prothrombin time, as well as factor X and factor IX activation.
Specific Inquiry
Figure 1 Binding of anti-TF antibodies to 6A6 coated on an ELISA plate.
Figure 2 Detection of anti-D3H44 antibodies in chimpanzees.
Chimpanzees were treated with D3H44-F(ab′)2 antibody. Plasma (citrated) samples were prepared from blood drawn before treatment with D3H44-F(ab′)2 antibody ("pre-treatment"), on day 21 and on day 43 post-treatment and analyzed for anti-D3H44 antibodies by competitive ELISA assay. 6A6 antibody or D3 antibody (control) were incubated with chimpanzee plasma and then the mixture was added to plates coated with D3H44-F(ab′)2 antibody. Bound chimpanzee antibodies were detected using anti-human Fc antibodies conjugated to horse radish peroxidase (HRP).
Specifications
- Immunogen
- Humanized Tissue factor
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TF
- Species Reactivity
- Human
- Clone
- 6A6
- Applications
- WB, ELISA, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for ELISA, Flow Cytometry, Inhibition and Function Assay. For details, refer to Published Data.
Target
- Alternative Names
- Factor VII; Factor VIIa; Tissue factor; TF
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-164 | Recombinant Mouse Anti-TF(Galβ1-3GalNAcα) Antibody (JAA-F11) | FuncS, IHC, FC, Cyt | IgG |
| MRO-1499-CN | Rabbit Anti-TF Recombinant Antibody (clone CBACN-552) | WB, IF, IHC | Rabbit IgG |
| MRO-1515-CN | Mouse Anti-TF Recombinant Antibody (clone D7-D11) | WB, IF | Mouse IgG2b |
| MRO-1516-CN | Mouse Anti-TF Recombinant Antibody (clone 4-E10) | WB, IHC, ELISA | Mouse IgM |
| MRO-1517-CN | Mouse Anti-TF Recombinant Antibody (clone A11-A3) | WB, IHC, ELISA | Mouse IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0510CL | Mouse Anti-TF Recombinant Antibody (TAB-0510CL) | WB, IF, ELISA | Mouse IgG |
| TAB-0510CL-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-0510CL-S(P)) | WB, IF, ELISA | Mouse scFv |
| TAB-0510CL-F(E) | Mouse Anti-TF Recombinant Antibody; Fab Fragment (TAB-0510CL-F(E)) | WB, IF, ELISA | Mouse Fab |
| TAB-598CT | Mouse Anti-TF Recombinant Antibody (TAB-598CT) | ELISA, FC | Mouse IgG1. κ |
| TAB-598CT-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-598CT-S(P)) | ELISA, FC | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-599CT | Anti-Human TF Recombinant Antibody (ATR-5) | ELISA, FC | Humanized antibody |
| TAB-600CT | Anti-Human TF Recombinant Antibody (ATR-2) | ELISA, FC | Humanized antibody |
| TAB-601CT | Anti-Human TF Recombinant Antibody (ATR-8) | ELISA, FC, BL | Humanized antibody |
| TAB-599CT-S(P) | Anti-Human TF Recombinant Antibody scFv Fragment (ATR-5) | ELISA, FC | Humanized antibody |
| TAB-600CT-S(P) | Anti-Human TF Recombinant Antibody scFv Fragment (ATR-2) | ELISA, FC | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-602CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (3e10) | ELISA, BL | Human antibody |
| TAB-603CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (3h2) | ELISA, BL | Human antibody |
| TAB-604CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2c1) | ELISA, BL | Human antibody |
| TAB-605CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2c11) | ELISA, BL | Human antibody |
| TAB-606CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2d3) | ELISA, BL | Human antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-175LC | Recombinant Anti-Human TF Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0860MZ | Chicken Anti-Transferrin Polyclonal IgY | ELISA | Chicken antibody |
MHC Tetramer for Other Applications
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1996CQ | Mouse Anti-TF Recombinant Antibody (clone HTF-14) | WB, Neut, ELISA, ICC, IF, IHC, IHC-P, RIA | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2022CQ | Mouse Anti-TF Recombinant Antibody (clone A68-B/A11) | ELISA, Inhib, IHC-P, IHC-Fr | Mouse IgM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3535 | Rabbit Anti-TF Recombinant Antibody (clone DS3535AB) | IHC-P, IP, WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0318CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone PTF.02); Fab Fragment | ELISA, FC | Mouse Fab |
| FAMAB-0319CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone TW4.20); Fab Fragment | ELISA, WB, FC, Inhib | Mouse Fab |
| HPAB-0767-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0767-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0768-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0768-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0769-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0769-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0207-YC-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (HPAB-M0207-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| HPAB-M0208-YC-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-M0208-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-M0209-YC-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-M0209-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-M0210-YC-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-M0210-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-0494-YJ-S(P) | Mouse Anti-TF Recombinant Antibody (clone CBT61YJ); scFv Fragment | ELISA, WB | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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