Afuco™ Anti-Human TGM2 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-585CL)
Anti-TGM2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). used in the treatment conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/635_D8_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/635_D8_3_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/639_D8_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/639_D8_2_blue_red_green.jpg
Figure 4 Colon
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/62634_A_9_3.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/62634_A_9_3.jpg
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000198959-TGM2
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000198959-TGM2
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198959-TGM2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198959-TGM2
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Celiac Disease; Scarring, Fibrosis-related Diseases; Neurodegenerative/Neurological Diseases; Cancer
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- TGM2; transglutaminase 2; TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h; protein-glutamine gamma-glutamyltransferase 2; TG(C); TGase C; TGase H; TGase-2; TGase-H; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; epididymis secretory protein Li 45; protein-glutamine-gamma-glutamyltransferase; C polypeptide, protein-glutamine-gamma-glutamyltransferase
- Gene ID
- 7052
- UniProt ID
- P21980
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B010(A) | Recombinant Anti-human TGM2 Intrabody [(D-Arg)9] | ELISA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B010(G) | Recombinant Anti-human TGM2 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B010(T) | Recombinant Anti-human TGM2 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-728 | Human Anti-TGM2 Recombinant Antibody (clone 679-14-E06); Fab Fragment | ELISA | Human Fab |
| HPAB-0313CQ-F(E) | Human Anti-TGM2 Recombinant Antibody (clone 2/A2); Fab Fragment | ELISA, IF | Human Fab |
| HPAB-AP806-YC-F(E) | Human Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP806-YC-F(E)) | ELISA, Inhib | Humanized Fab |
| HPAB-AP807-YC-F(E) | Human Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP807-YC-F(E)) | ELISA, Inhib | Humanized Fab |
| HPAB-AP808-YC-F(E) | Mouse Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP808-YC-F(E)) | ELISA, Inhib | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-728 | Human Anti-TGM2 Recombinant Antibody (clone 679-14-E06); scFv Fragment | ELISA | Human scFv |
| HPAB-0313CQ-S(P) | Human Anti-TGM2 Recombinant Antibody (clone 2/A2); scFv Fragment | ELISA, IF | Human scFv |
| HPAB-AP806-YC-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP806-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-AP807-YC-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP807-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-AP808-YC-S(P) | Mouse Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP808-YC-S(P)) | ELISA, Inhib | Mouse scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-629CT | Human Anti-TGM2 Recombinant Antibody (TAB-629CT) | ELISA, WB, FC | Human antibody |
| TAB-630CT | Human Anti-TGM2 Recombinant Antibody (TAB-630CT) | ELISA, WB, FC | Human antibody |
| TAB-631CT | Human Anti-TGM2 Recombinant Antibody (TAB-631CT) | ELISA, WB, FC | Human antibody |
| TAB-629CT-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (TAB-629CT-S(P)) | ELISA, WB, FC | Human scFv |
| TAB-630CT-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (TAB-630CT-S(P)) | ELISA, WB, FC | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1819CT | Recombinant Mouse anti-Human TGM2 Monoclonal antibody (2A1) | ELISA, WB | |
| MRO-1525-CN | Rabbit Anti-TGM2 Recombinant Antibody (clone JU30-02) | WB, IHC, IP | Rabbit IgG |
| HPAB-AP806-YC | Human Anti-TGM2 Recombinant Antibody (HPAB-AP806-YC) | ELISA, Inhib | Humanized IgG |
| ZG-0592U | Rabbit Anti-TGM2 Recombinant Antibody (clone 7E1) | ELISA, WB | Rabbit IgG |
| VS3-FY1448 | Recombinant Rabbit Anti-TGM2 Antibody (clone R07-8K1) | WB, IHC-P, IP | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3555 | Rabbit Anti-TGM2 Recombinant Antibody (clone DS3555AB) | IHC-P, IP, WB | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0081LC | Mouse Anti-TGM2 Recombinant Antibody (clone 40) | ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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