Recombinant Anti-human TGM2 Intrabody [+36 GFP]
CAT#: IAB-B010(G)
Recombinant anti-TGM2 intrabody in fusion with +36GFP works within cells and directes to antigen human TGM2, expressed in CHO cells. The intracellular antibody can inhibit the ransglutaminase activity may be by one or more techniques, including, but not limited to, downregulating transglutaminase expression, inhibiting TG2 translation, or blocking TG2 enzymatic activity.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/635_D8_3_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/639_D8_2_blue_red_green.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/62634_A_9_3.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198959-TGM2
❮
❯
Specifications
- Immunogen
- human transglutaminase 2
- Host Species
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Antibody assay: Protein fragment complementation; Western blot; Functional studies
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- TGM2; transglutaminase 2; TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h; protein-glutamine gamma-glutamyltransferase 2; TG(C); TGase C; TGase H; TGase-2; TGase-H; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; epididymis secret
- Gene ID
- 7052
- UniProt ID
- P21980
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-AP808-YC | Mouse Anti-TGM2 Recombinant Antibody (HPAB-AP808-YC) | ELISA, Inhib | Mouse IgG |
| HPAB-AP809-YC | Mouse Anti-TGM2 Recombinant Antibody (HPAB-AP809-YC) | ELISA, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-728 | Human Anti-TGM2 Recombinant Antibody (clone 679-14-E06); Fab Fragment | ELISA | Human Fab |
| HPAB-AP810-YC-F(E) | Mouse Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP810-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-AP811-YC-F(E) | Mouse Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP811-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-AP812-YC-F(E) | Mouse Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP812-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-AP813-YC-F(E) | Mouse Anti-TGM2 Recombinant Antibody; Fab Fragment (HPAB-AP813-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-629CT-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (TAB-629CT-S(P)) | ELISA, WB, FC | Human scFv |
| TAB-630CT-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (TAB-630CT-S(P)) | ELISA, WB, FC | Human scFv |
| TAB-631CT-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (TAB-631CT-S(P)) | ELISA, WB, FC | Human scFv |
| TAB-629CT-F(E) | Human Anti-TGM2 Recombinant Antibody; Fab Fragment (TAB-629CT-F(E)) | ELISA, WB, FC | Human Fab |
| TAB-630CT-F(E) | Human Anti-TGM2 Recombinant Antibody; Fab Fragment (TAB-630CT-F(E)) | ELISA, WB, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3555 | Rabbit Anti-TGM2 Recombinant Antibody (clone DS3555AB) | IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0081LC | Mouse Anti-TGM2 Recombinant Antibody (clone 40) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP806-YC-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP806-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-AP807-YC-S(P) | Human Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP807-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-AP808-YC-S(P) | Mouse Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP808-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| HPAB-AP809-YC-S(P) | Mouse Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP809-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| HPAB-AP810-YC-S(P) | Mouse Anti-TGM2 Recombinant Antibody; scFv Fragment (HPAB-AP810-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1330 | AbPlus™ Anti-TGM2 Magnetic Beads (VS-0724-YC1330) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC96 | Rabbit Anti-TGM2 Antibody (VS-0924-YC96) - Cancer Stem Cell Marker | IHC, WB, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY512 | Mouse Anti-NHP TGM2 Recombinant Antibody (clone SPM358) | WB, IHC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY76 | Human Anti-TGM2 (clone 679-14-E06) scFv-Fc Chimera | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2279 | Anti-TGM2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7221 | Anti-Mouse TGM2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7220 | Anti-Human TGM2 Immunohistochemistry Kit | IHC |
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