Recombinant Anti-human TGM2 Intrabody [+36 GFP] (CAT#: IAB-B010(G))
Recombinant anti-TGM2 intrabody in fusion with +36GFP works within cells and directes to antigen human TGM2, expressed in CHO cells. The intracellular antibody can inhibit the ransglutaminase activity may be by one or more techniques, including, but not limited to, downregulating transglutaminase expression, inhibiting TG2 translation, or blocking TG2 enzymatic activity.
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Custom Production
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/635_D8_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/635_D8_3_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/639_D8_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2598/639_D8_2_blue_red_green.jpg
Figure 4 Colon
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/62634_A_9_3.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29518/62634_A_9_3.jpg
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000198959-TGM2
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000198959-TGM2
Figure 5 RNA cell line category: Group enriched (CAPAN-2, EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198959-TGM2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198959-TGM2
Specifications
- Immunogen
- human transglutaminase 2
- Host Species
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Antibody assay: Protein fragment complementation; Western blot; Functional studies
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- TGM2; transglutaminase 2; TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h; protein-glutamine gamma-glutamyltransferase 2; TG(C); TGase C; TGase H; TGase-2; TGase-H; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; epididymis secret
- Gene ID
- 7052
- UniProt ID
- P21980
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1191z | Mouse Anti-TGM2 Recombinant Antibody (clone 20C5) | FC, ICC, IF, IHC | Mouse IgG2a, κ |
| HPAB-0313CQ | Human Anti-TGM2 Recombinant Antibody (clone 2/A2) | Cyt, FuncS, ELISA, Inhib | Human IgG |
| HPAB-AP806-YC | Human Anti-TGM2 Recombinant Antibody (HPAB-AP806-YC) | ELISA, Inhib | Humanized IgG |
| HPAB-AP807-YC | Human Anti-TGM2 Recombinant Antibody (HPAB-AP807-YC) | ELISA, Inhib | Humanized IgG |
| HPAB-AP808-YC | Mouse Anti-TGM2 Recombinant Antibody (HPAB-AP808-YC) | ELISA, Inhib | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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