Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); Fab Fragment (CAT#: HPAB-0174-YC-F(E))
Tissue inhibitors of metalloproteases (TIMPs) inhibit metalloproteases, a family of endopeptide hydrolases. Metalloproteases are secreted by connective tissue and hematopoietic cells, use Zn2+ or Ca2+ for catalysis, and may be inactivated by metal chelators as well as TIMP molecules. Matrix metalloproteases (MMPs) participate in a variety of biologically important processes, including the degradation of many structural components of tissues, particularly the extracellular matrix (ECM).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22360/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22360/if_selected.jpg
Figure 2 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/ihc_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_7_5.jpg
Figure 4 Prostate
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_2_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53417/139501_A_2_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102265-TIMP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102265-TIMP1
Specifications
- Host Species
- Human
- Derivation
- Human antibody library
- Type
- Human Fab
- Specificity
- Human TIMP1
- Species Reactivity
- Human
- Clone
- HuCAL
- Applications
- ELISA
- Related Disease
- Liver fibrosis, Alcoholic liver disease, Cardiac fibrosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone HuCAL"
See other products for "TIMP1"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Human Antibody Products
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
ScFv Antibody Products
Fab Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1378z | Mouse Anti-TIMP1 Recombinant Antibody (clone 39D12) | WB, ELISA | Mouse IgG1 |
| HPAB-0174-YC | Human Anti-TIMP1 Recombinant Antibody (clone HuCAL) | ELISA | Human IgG |
| ZG-0705F | Mouse Anti-TIMP1 Recombinant Antibody (clone 2A5) | WB, ELISA, IHC | Mouse IgG1 |
| ZG-0154U | Mouse Anti-Timp1 Recombinant Antibody (clone 4A2B1) | ELISA, IHC | Mouse IgG1 |
| ZG-0205U | Mouse Anti-TIMP1 Recombinant Antibody (clone 8B4E9) | ELISA, WB, IHC | Mouse IgG2a |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0174-YC-F(E). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, Inhib, FuncS
Application: ELISA, FuncS, Neut, IF, WB, EM, Inhib, IHC
Application: ELISA, FC
-3.jpg)
Application: IB, FC, ELISA, FuncS
Application: ELISA, FC, FuncS
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
