Afuco™ Anti-Human TLR3 ADCC Recombinant Antibody (IPH33), ADCC Enhanced
CAT#: AFC-590CL
Anti-TLR3 ADCC Enhanced Antibody (IPH33) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH33 is a monoclonal antibody targeting the Toll-like Receptor-3 receptor (TLR3), it can be used in a broad spectrum of chronic inflammatory indications, such as COPD, IBD, RA.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_B_8_5.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids
Staining: Medium
Intensity: Strong
Quantity: <25%
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_4_6.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids Staining: Medium Intensity: Strong Quantity: <25% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164342-TLR3
Normal Tissue
Figure 2 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_9_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164342-TLR3
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FuncS
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Applications
- Application Notes
- The antibody was validated for Function Assay. For details, refer to Published Data.
Target
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Related Signaling Pathways
NLR Signaling Pathway
TLR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-687CT | Mouse Anti-TLR3 Recombinant Antibody (TAB-687CT) | ELISA, FC, Inhib | Mouse IgG |
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|---|---|---|---|
| BRD-0589MZ | Chicken Anti-TLR3 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0725-CN-S(P) | Human Anti-TLR3 Recombinant Antibody; scFv Fragment (HPAB-0725-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-1034WJ-S(P) | Mouse Anti-TLR3 Recombinant Antibody; scFv Fragment (HPAB-1034WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1035WJ-S(P) | Mouse Anti-TLR3 Recombinant Antibody; scFv Fragment (HPAB-1035WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1036WJ-S(P) | Mouse Anti-TLR3 Recombinant Antibody; scFv Fragment (HPAB-1036WJ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1037WJ-S(P) | Mouse Anti-TLR3 Recombinant Antibody; scFv Fragment (HPAB-1037WJ-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0725-CN-F(E) | Human Anti-TLR3 Recombinant Antibody; Fab Fragment (HPAB-0725-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-1034WJ-F(E) | Mouse Anti-TLR3 Recombinant Antibody; Fab Fragment (HPAB-1034WJ-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-1035WJ-F(E) | Mouse Anti-TLR3 Recombinant Antibody; Fab Fragment (HPAB-1035WJ-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-1036WJ-F(E) | Mouse Anti-TLR3 Recombinant Antibody; Fab Fragment (HPAB-1036WJ-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-1037WJ-F(E) | Mouse Anti-TLR3 Recombinant Antibody; Fab Fragment (HPAB-1037WJ-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY213 | CytoStream™ Mouse Anti-TLR3 Recombinant Antibody (VS-0225-XY213) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY7 | Mouse Anti-TLR3 scFv-Fc Chimera (VS-0425-FY7) | ELISA, FC, IHC, Inhib | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC530 | Recombinant Anti-TLR3 Vesicular Antibody, EV Displayed (VS-0425-YC530) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7303 | Anti-TLR3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7304 | Anti-Mouse TLR3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7305 | Anti-Canine TLR3 Immunohistochemistry Kit | IHC |
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