Afuco™ Anti-Human TLR3 ADCC Recombinant Antibody (IPH33), ADCC Enhanced (CAT#: AFC-590CL)

Anti-TLR3 ADCC Enhanced Antibody (IPH33) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH33 is a monoclonal antibody targeting the Toll-like Receptor-3 receptor (TLR3), it can be used in a broad spectrum of chronic inflammatory indications, such as COPD, IBD, RA.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FuncS

Figure 1 show results of drug combinations with anti-human TLR3 mAbs (labeled IPH33.1) in combination with dexamethasone or Humira® respectively.

Figure 1 show results of drug combinations with anti-human TLR3 mAbs (labeled IPH33.1) in combination with dexamethasone or Humira® respectively.

Antibodies each substantially reduce in vitro IP-10 production by PBMC in response to polylC further when combined with dexamethasone or Humira®.


Specifications

  • Host Species
  • Humanized
  • Derivation
  • Humanized
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • FuncS
  • Related Disease
  • Inflammatory Diseases

Product Property

  • Purity
  • >90% assessed by SDS-PAGE
  • Storage
  • Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.

Applications

  • Application Notes
  • The antibody was validated for Function Assay. For details, refer to Published Data.

Target

  • Alternative Names
  • TLR3; toll-like receptor 3; CD283; IIAE2

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TLR3"

Humanized Antibody

CAT Product Name Application Type
TAB-612CL Human Anti-TLR3 Recombinant Antibody (TAB-612CL) ELISA Human IgG

Mouse Antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0589MZ Chicken Anti-TLR3 Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2035CQ Mouse Anti-TLR3 Recombinant Antibody (clone TLR3.7) FC, FuncS, Neut Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4459 Rabbit Anti-TLR3 Recombinant Antibody (clone SI553DS) ELISA Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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