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    Afuco™ Anti-Human TLR3 ADCC Recombinant Antibody (IPH33), ADCC Enhanced (CAT#: AFC-590CL)

    Anti-TLR3 ADCC Enhanced Antibody (IPH33) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH33 is a monoclonal antibody targeting the Toll-like Receptor-3 receptor (TLR3), it can be used in a broad spectrum of chronic inflammatory indications, such as COPD, IBD, RA.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_B_8_5.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_9_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_8_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Elongated or late spermatids
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_4_6.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Elongated or late spermatids Staining: Medium Intensity: Strong Quantity: <25% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_4_6.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25658/59668_A_9_3.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
    Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164342-TLR3
    Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
    Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, CAPAN-2, HDLM-2, HSkMC)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164342-TLR3

    Specifications

    • Host Species
    • Humanized
    • Derivation
    • Humanized
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • FuncS
    • Related Disease
    • Inflammatory Diseases

    Product Property

    • Purity
    • >90% assessed by SDS-PAGE
    • Storage
    • Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.

    Applications

    • Application Notes
    • The antibody was validated for Function Assay. For details, refer to Published Data.

    Target

    • Alternative Names
    • TLR3; toll-like receptor 3; CD283; IIAE2

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TLR3"

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    CAT Product Name Application Type
    MOB-1476z Mouse Anti-TLR3 Recombinant Antibody (clone 40D4) WB, ICC, IF, IHC, IP, FuncS Mouse IgG1
    HPAB-0725-CN Human Anti-TLR3 Recombinant Antibody (HPAB-0725-CN) ELISA, FC Human IgG4
    HPAB-1034WJ Mouse Anti-TLR3 Recombinant Antibody (HPAB-1034WJ) ELISA, FC Mouse IgG
    HPAB-1035WJ Mouse Anti-TLR3 Recombinant Antibody (HPAB-1035WJ) ELISA, FC Mouse IgG
    VS3-QX1127 Mouse Anti-TLR3 Recombinant Antibody (clone 2F10-B8-G9) WB Mouse IgG2b

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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