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  • Afuco™ Anti-Human TMPRSS4 ADCC Recombinant Antibody, ADCC Enhanced

Afuco™ Anti-Human TMPRSS4 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-599CL)

Anti-TMPRSS4 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-ovarian antibodies that bind to Ovr115 are used in treating pancreatic, lung or breast cancer.

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Normal Tissue
Figure 1 IHC staining of human urinary bladder
Figure 1 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows cytoplasmic positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_4_5_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_7_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6238/17853_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (CAPAN-2, HaCaT, OE19, RPTEC TERT1, RT4)
Figure 8 RNA cell line category: Group enriched (CAPAN-2, HaCaT, OE19, RPTEC TERT1, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137648-TMPRSS4

Specifications

  • Host Species
  • Humanized
  • Derivation
  • Humanized
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Cancer

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Target

  • Alternative Names
  • TMPRSS4; transmembrane protease, serine 4; CAPH2; MT-SP2; TMPRSS3; transmembrane protease serine 4; channel-activating protease 2; membrane-type serine protease 2; transmembrane serine protease 3; type II membrane serine protease

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Please select product type
Human Antibody Products Mouse Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products
CAT Product Name Application Type
TAB-720CT Human Anti-TMPRSS4 Recombinant Antibody (TAB-720CT) WB, ELISA Human antibody
TAB-721CT Human Anti-TMPRSS4 Recombinant Antibody (TAB-721CT) WB, ELISA Human antibody
TAB-722CT Human Anti-TMPRSS4 Recombinant Antibody (TAB-722CT) WB, ELISA Human antibody
TAB-720CT-S(P) Human Anti-TMPRSS4 Recombinant Antibody; scFv Fragment (TAB-720CT-S(P)) WB, ELISA Human scFv
TAB-721CT-S(P) Human Anti-TMPRSS4 Recombinant Antibody; scFv Fragment (TAB-721CT-S(P)) WB, ELISA Human scFv

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Boosts Cancer Research Potential
This antibody has greatly enhanced our research capabilities by providing clearer insights into TMPRSS4-related pathways. Its ADCC properties help us explore how immune responses can be manipulated to develop more effective cancer treatments.

Versatile Application in Studies
We've found this antibody very versatile, suitable for a range of assays like ELISA and flow cytometry. Its high purity ensures that our results are consistent and reproducible, which is crucial for validating our experimental findings.

Enhances Immune Research
The ADCC enhancement has transformed how we study immune interactions with cancer cells. This antibody's ability to amplify immune responses helps clarify mechanisms of tumor resistance, guiding our research towards potential immunotherapy strategies.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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