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    Anti-Human TNF alpha Recombinant Antibody Fab Fragment (TAB-034-F(E)) (CAT#: TAB-034-F(E))

    Recombinant antibody Fragment Fab to TNF alpha. It is a monoclonal antibody directed against tumor necrosis factor alpha. More precisely, it is a PEGylated Fab' fragment of a humanized TNF inhibitor monoclonal antibody. Polyethylene glycol does not cross the placenta, so it should be safe in pregnancy.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Tonsil
    Figure 1 Tonsil
    (Germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
    RNA Expression
    Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
    Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000232810-TNF
    Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
    Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Mouse
    • Derivation
    • Humanized (from mouse)
    • Type
    • Fab'
    • Specificity
    • Tested positive against native human antigen.
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FC, IP, FuncS, IF, Neut, IHC, Activ, Inhib
    • MW
    • 47.75 kDa
    • Related Disease
    • Psoriatic arthritis (PSA)

    Product Property

    • Purity
    • >95.0% as determined by analysis by SDS-PAGE.
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Applications

    • Application Notes
    • The TNF antibody has been reported in applications of ELISA, FC, IP, FuncS, IF, Neut, IHC, Activ, Inhib.

    Target

    • Alternative Names
    • Certolizumab pegol;cimzia;428863-50-7;CDP870;PHA-738144;TNF;tumor necrosis factor;TNFA, tumor necrosis factor (TNF superfamily, member 2);DIF;TNF superfamily;member 2;TNF alpha;TNFSF2;TNF-a;cachectin;APC1 protein;TNF, monocyte-derived;TNF, macrophage-deri

    Related Resources

    • Biosimilar Overview
    • Related Diseases
    • Related Signaling Pathways
    Please refer to Certolizumab Pegol Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Certolizumab Pegol.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TNF"

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    CAT Product Name Application Type
    TAB-010 Anti-Human TNF Recombinant Antibody (TAB-010) WB, FC, IP, ELISA, Neut, FuncS, IF IgG1, κ
    TAB-396CQ Anti-Human TNF Recombinant Antibody (TAB-396CQ) ELISA Human antibody
    TAB-397CQ Human Anti-TNF Recombinant Antibody (TAB-397CQ) ELISA Human IgG
    TAB-398CQ Anti-Human TNF Recombinant Antibody (TAB-398CQ) ELISA Human antibody
    TAB-399CQ Anti-Human TNF Recombinant Antibody (TAB-399CQ) WB Human antibody

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    Cite This Product

    To accurately reference this product in your publication, please use the following citation information:

    (Creative Biolabs Cat# TAB-034-F(E), RRID: AB_3111767)

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