Anti-Human TNFRSF12A Recombinant Antibody (TPP-883)
CAT#: TAB-221CQ
The antibody is specific for the TWEAKR and can be potentially used in the treatment of tumors.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_B_7_5.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Trophoblastic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_2_7.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (U-251 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006327-TNFRSF12A
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Specifications
- Host Species
- Human
- Derivation
- Dyax antibody library
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- TPP-883
- Applications
- ELISA, FC, WB
- Related Disease
- Tumors
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry, Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; FN14; CD266; TWEAKR; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14
- Gene ID
- 51330
- UniProt ID
- Q9NP84
REVIEWS AND Q&AS
CITATIONS
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Customer Review
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Great for Cancer Research
This antibody has been a valuable tool in our cancer research projects. We use it to study how TNFRSF12A affects tumor growth. Its high specificity and purity have provided us with accurate data, helping us understand cancer cell behavior better.
User-Friendly
As someone new to protein detection, I found this antibody very user-friendly. The provided protocols were easy to follow, and the technical support was helpful. I was able to successfully detect TNFRSF12A in our cell samples with confidence.
Excellent Support
The customer service and technical support for this product have been excellent. They provided detailed answers to our questions and helped optimize our protocols. This support has made using the antibody a positive experience.
Q&As
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How can I use this antibody in my research?
A: You can use this antibody in various experiments to study cell functions. It's great for applications like Western blotting, ELISA, and flow cytometry. It helps you detect the TNFRSF12A protein in your samples, allowing you to explore its role in diseases like cancer and inflammation.
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Does the antibody come with any additional support or services?
A: Yes, technical support is available to help you make the most of this antibody in your research. The supplier can provide protocols and guidance on how to use the antibody effectively in your experiments, ensuring you get reliable and reproducible results.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone TPP-883"
- CAT
- Product Name
See other products for "TNFRSF12A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G061G | Anti-TNFRSF12A immunotoxin ITEM-4 (scFv)-Gel | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219CQ-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-219CQ-S(P)) | ELISA, FC, IHC | Humanized scFv |
| TAB-225CQ-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-225CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-219CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-219CQ-F(E)) | ELISA, FC, IHC | Humanized Fab |
| TAB-225CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-225CQ-F(E)) | ELISA, FC | Humanized Fab |
| TAB-227CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-227CQ-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-220CQ-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (TAB-220CQ-S(P)) | ELISA, FC, IHC | Mouse scFv |
| TAB-220CQ-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-220CQ-F(E)) | ELISA, FC, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-221CQ-S(P) | Anti-Human TNFRSF12A Recombinant Antibody scFv Fragment (TPP-883) | ELISA, FC, WB | Human antibody |
| TAB-221CQ-F(E) | Anti-Human TNFRSF12A Recombinant Antibody Fab Fragment (TPP-883) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218CQ-F(E) | Mouse Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-218CQ-F(E)) | ELISA, FC, IHC | Mouse Fab |
| TAB-222CQ-F(E) | Mouse Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-222CQ-F(E)) | ELISA, FC | Mouse Fab |
| TAB-223CQ-F(E) | Mouse Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-223CQ-F(E)) | ELISA, FC | Mouse Fab |
| TAB-224CQ-F(E) | Chicken Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-224CQ-F(E)) | ELISA, FC | Chicken Fab |
| TAB-226CQ-F(E) | Chicken Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (TAB-226CQ-F(E)) | ELISA, FC | Chicken Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-194LC | Recombinant Anti-Human TNFRSF12A Antibody (Non-glycosylated) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3610 | Rabbit Anti-TNFRSF12A Recombinant Antibody (clone DS3610AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0048-LSX | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-883) | ELISA, WB, FC | Human IgG |
| HPAB-0049-LSX | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2090) | ELISA, WB, FC, FuncS | Human IgG |
| HPAB-0050-LSX | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2658) | ELISA, WB, FC | Human IgG |
| HPAB-0051-LSX | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2084) | ELISA, WB, FC, FuncS | Human IgG |
| HPAB-0052-LSX | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-1104) | ELISA, WB, FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0048-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-883); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0049-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2090); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0050-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2658); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0051-LSX-F(E) | Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-2084); Fab Fragment | ELISA, WB, FC | Human Fab |
| HPAB-0559-FY-F(E) | Human Anti-TNFRSF12A Recombinant Antibody; Fab Fragment (HPAB-0559-FY-F(E)) | Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0112LY-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0112LY-S(P)) | ELISA | Humanized scfv |
| HPAB-0113LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0113LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0114LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0114LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0115LY-S(P) | Mouse Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0115LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0116LY-S(P) | Human Anti-TNFRSF12A Recombinant Antibody; scFv Fragment (HPAB-0116LY-S(P)) | ELISA | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY191 | Human Anti-TNFRSF12A (clone TPP-883) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC657 | Recombinant Anti-TNFRSF12A Vesicular Antibody, EV Displayed (VS-0425-YC657) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7370 | Anti-TNFRSF12A Immunohistochemistry Kit | IHC | |
| VS-0525-XY7371 | Anti-Mouse TNFRSF12A Immunohistochemistry Kit | IHC |
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