Human Anti-TNFRSF17 Recombinant Antibody (TAB-1219CL) (CAT#: TAB-1219CL)
This product is a recombinant human antibody that recognizes BCMA (CD269, TNFRSF17). The chimeric antibody binds to the extracellular domain of human BCMA and disrupt the interaction between BCMA and native ligands BAFF and APRIL. The antibody was initially ascertained by ELISA and flow cytometry on the human multiple myeloma cell line MM.1 S. The affinity to BCMA was 54 pM as determined using surface plasmon resonance (SPR).
Specific Inquiry
DB
Figure 1 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in DB
Antigen: Recombinant human TNFRSF17 protein
Antibody incubation concentration: 2ng/μL.
The secondary antibody: HRP-conjugated goat anti-human IgG
ELISA
Figure 2 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in ELISA
ELISA analysis of TAB-1219CL was performed by coating with Recombinant Human TNFRSF17 Protein. Then blocked with BSA, and incubated with Anti-Human TNFRSF17 Antibody (TAB-1219CL). The HRP-conjugated goat Anti-Human IgG was used as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (Mouse/Human)
- Type
- Chimeric (Mouse/Human) IgG1
- Specificity
- Human TNFRSF17
- Species Reactivity
- Human
- Applications
- ELISA, FC, Block, Cyt, FuncS
- Related Disease
- Multiple myeloma, Autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein;
- Gene ID
- 608
- UniProt ID
- Q02223
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Blocking Antibody Products
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-019 | Mouse Anti-TNFRSF17 Recombinant Antibody (clone J22.9-xi); Fab Fragment | Neut, FuncS | Mouse Fab |
| HPAB-1869LY-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1869LY-F(E)) | ELISA | Human Fab |
| HPAB-1870LY-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1870LY-F(E)) | ELISA | Human Fab |
| HPAB-1871LY-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1871LY-F(E)) | ELISA | Human Fab |
| HPAB-1872LY-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1872LY-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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