Human Anti-TNFRSF17 Recombinant Antibody (TAB-1219CL)

Name: Human Anti-TNFRSF17 Recombinant Antibody (TAB-1219CL)
SKU: TAB-1219CL
Rating: 5 (1 reviews)

CAT#: TAB-1219CL

This product is a recombinant human antibody that recognizes BCMA (CD269, TNFRSF17). The chimeric antibody binds to the extracellular domain of human BCMA and disrupt the interaction between BCMA and native ligands BAFF and APRIL. The antibody was initially ascertained by ELISA and flow cytometry on the human multiple myeloma cell line MM.1 S. The affinity to BCMA was 54 pM as determined using surface plasmon resonance (SPR).

Tested Data Gene Expression

Figure 1 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in DB

Antigen: Recombinant human TNFRSF17 protein
Antibody incubation concentration: 2ng/μL.
The secondary antibody: HRP-conjugated goat anti-human IgG

ELISA

Figure 2 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in ELISA

ELISA analysis of TAB-1219CL was performed by coating with Recombinant Human TNFRSF17 Protein. Then blocked with BSA, and incubated with Anti-Human TNFRSF17 Antibody (TAB-1219CL). The HRP-conjugated goat Anti-Human IgG was used as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.

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RNA Expression Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, U-266/70, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000048462-TNFRSF17

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Specifications

Host Species
Human

Derivation
Chimeric (Mouse/Human)

Type
Chimeric (Mouse/Human) IgG1

Specificity
Human TNFRSF17

Species Reactivity
Human

Applications
ELISA, FC, Block, Cyt, FuncS

Related Disease
Multiple myeloma, Autoimmune diseases

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein;

Gene ID
608

UniProt ID
Q02223

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-1219CL.pdf

MSDS

MSDS - TAB-1219CL.pdf

COA

Certificate of Analysis Lookup

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CAT	Product Name	Application	Type
TAB-1208CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1208CL-S(P))	ELISA, FC	Human scFv
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TAB-1210CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1210CL-S(P))	ELISA, FC	Human scFv
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TAB-1212CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1212CL-S(P))	ELISA, FC	Human scFv

CAT	Product Name	Application	Type
TAB-1219CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1219CL-S(P))	ELISA, FC, Block, FuncS	Human scFv
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TAB-1227CL-S(P)	Mouse Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1227CL-S(P))	FuncS	Mouse scFv
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CAT	Product Name	Application	Type
TAB-1220CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1220CL-S(P))	ELISA	Human scFv
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TAB-1231CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1231CL-S(P))	ELISA	Humanized scFv
TAB-1232CL-S(P)	Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1232CL-S(P))	ELISA	Humanized scFv
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CAT	Product Name	Application	Type
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HPAB-1870LY-F(E)	Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1870LY-F(E))	ELISA	Human Fab
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HPAB-1872LY-F(E)	Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-1872LY-F(E))	ELISA	Human Fab
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