Human Anti-TNFRSF17 Recombinant Antibody (TAB-1219CL) (CAT#: TAB-1219CL)

This product is a recombinant human antibody that recognizes BCMA (CD269, TNFRSF17). The chimeric antibody binds to the extracellular domain of human BCMA and disrupt the interaction between BCMA and native ligands BAFF and APRIL. The antibody was initially ascertained by ELISA and flow cytometry on the human multiple myeloma cell line MM.1 S. The affinity to BCMA was 54 pM as determined using surface plasmon resonance (SPR).


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DB

Figure 1 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in DB

Figure 1 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in DB

Antigen: Recombinant human TNFRSF17 protein
Antibody incubation concentration: 2ng/μL.
The secondary antibody: HRP-conjugated goat anti-human IgG

ELISA

Figure 2 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in ELISA

Figure 2 Human Anti-Human TNFRSF17 Recombinant Antibody (TAB-1219CL) in ELISA

ELISA analysis of TAB-1219CL was performed by coating with Recombinant Human TNFRSF17 Protein. Then blocked with BSA, and incubated with Anti-Human TNFRSF17 Antibody (TAB-1219CL). The HRP-conjugated goat Anti-Human IgG was used as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.


Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric (Mouse/Human)
  • Type
  • Chimeric (Mouse/Human) IgG1
  • Specificity
  • Human TNFRSF17
  • Species Reactivity
  • Human
  • Applications
  • ELISA, FC, Block, Cyt, FuncS
  • Related Disease
  • Multiple myeloma, Autoimmune diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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