Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-0372CL-F(E))

Name: Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-0372CL-F(E))
SKU: TAB-0372CL-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-0372CL-F(E)

This product is a recombinant human antibody Fab fragment that recognizes AITR (glucocorticoid-induced TNFR-related protein, GITR). The antibody was purified by affinity chromatography.

Gene Expression

Normal Tissue Figure 1 IHC staining of human spleen

Immunohistochemical staining of human spleen shows moderate cytoplasmic positivity in red pulp and cells in white pulp.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_9_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_3.jpg

Normal Tissue Figure 4 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_5_6.jpg

Normal Tissue Figure 6 Bone marrow

Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_4_4.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_8_8.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (RPMI-8226, SCLC-21H)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186891-TNFRSF18

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Specifications

Immunogen
Human AITR-GST fusion protein

Host Species
Human

Type
Human Fab

Specificity
Human AITR (glucocorticoid-induced TNFR-related protein, GITR)

Species Reactivity
Human

Applications
ELISA, WB, FuncS, FC, IP

Related Disease
Lung carcinoma, immune response, tumor necrosis, autoimmune diseases

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
See the COA

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
TNFRSF18; tumor necrosis factor receptor superfamily, member 18; AITR; GITR; CD357; GITR-D; tumor necrosis factor receptor superfamily member 18; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein

Gene ID
8784

UniProt ID
Q9Y5U5

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0372CL-F(E).pdf

MSDS

MSDS - TAB-0372CL-F(E).pdf

COA

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