Human Anti-TNFRSF18 Recombinant Antibody (TAB-0368CL) (CAT#: TAB-0368CL)
This product is a recombinant human antibody that specifically binds to AITR. The antibody originally was selected from a human antibody library. The epitope for anti-AITR antibody is located in the amino acid 56-65, HCGDPCCTTC.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows moderate cytoplasmic positivity in red pulp and cells in white pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows moderate cytoplasmic positivity in red pulp and cells in white pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/ihc_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_9_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_5.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_5_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_5_6.jpg
Figure 6 Bone marrow
(Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_4_4.jpg
(Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_4_4.jpg
Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_8_8.jpg
Figure 8 RNA cell line category: Group enriched (RPMI-8226, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186891-TNFRSF18
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186891-TNFRSF18
Specifications
- Immunogen
- Human AITR-GST fusion protein
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human AITR (glucocorticoid-induced TNFR-related protein, GITR)
- Species Reactivity
- Human
- Applications
- ELISA, WB, FuncS, FC, IP
- Related Disease
- Lung carcinoma, immune response, tumor necrosis, autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFRSF18; tumor necrosis factor receptor superfamily, member 18; AITR; GITR; CD357; GITR-D; tumor necrosis factor receptor superfamily member 18; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein
- Gene ID
- 8784
- UniProt ID
- Q9Y5U5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3604z | Mouse Anti-TNFRSF18 Recombinant Antibody (clone 41H7) | WB, ELISA, IHC | Mouse IgG2b |
| HPAB-0052-LS | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-0052-LS) | ELISA, FC, FuncS | Humanized IgG1, κ |
| HPAB-0053-LS | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-0053-LS) | ELISA, FC, FuncS | Humanized IgG1, κ |
| HPAB-N0397-YC | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-N0397-YC) | ELISA, FC | Human IgG4 |
| HPAB-0257-FY | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-0257-FY) | FC, Inhib | Chimeric (mouse/human) IgG1 |
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