Mouse Anti-TNFRSF6B Recombinant Antibody (clone 4V24)
CAT#: NEUT-2162CQ
This antibody is a mouse monoclonal antibody that binds specifically to DcR3, and it can neutralize the bioactivity of DcR3.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human appendix
Immunohistochemical staining of human appendix shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47154/109311_A_1_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47154/109311_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47154/109311_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47154/109311_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47154/109311_A_7_5.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HBEC3-KT, RPTEC TERT1, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000243509-TNFRSF6B
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Specifications
- Immunogen
- Recombinant human TNFRSF6B
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human TNFRSF6B
- Species Reactivity
- Human
- Clone
- 4V24
- Applications
- Neut, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Effective Neutralization Of DcR3
We utilized this mouse monoclonal antibody to neutralize the bioactivity of DcR3 (TNFRSF6B). It effectively competed with ligands in our assay, confirming its neutralizing capability. This product is essential for our research into decoy receptor functions.
Clear Western Blot
We also used this antibody for Western Blotting to detect TNFRSF6B expression. The antibody (clone 4V24) yielded specific bands for the human protein. It is a high-quality reagent that we store at -20°C for long-term use.
Q&As
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What is the alternative name for the target of this antibody?
A: The target of this antibody, TNFRSF6B, is also commonly known as DcR3 (Decoy receptor 3). It binds to this protein, which acts as a decoy receptor for FasL and LIGHT, competing with death receptors for ligand binding.
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What is the isotype of this antibody?
A: This is a Mouse monoclonal antibody with an IgG1 isotype. It is a recombinant antibody (Clone 4V24) purified by Protein G affinity chromatography. It is suitable for Neutralization and Western Blot applications.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TNFRSF6B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1963z | Mouse Anti-TNFRSF6B Recombinant Antibody (clone 23F7) | WB, ELISA, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1352MZ | Recombinant Mouse Anti-Human TNFRSF6B Antibody (clone 7G5) | IHC-P, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2163CQ | Mouse Anti-TNFRSF6B Recombinant Antibody (clone CBL727) | Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2164CQ | Mouse Anti-TNFRSF6B Recombinant Antibody (clone CBL051) | WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-0425-WR1022 | Mouse Anti-TNFRSF6B Recombinant Antibody (clone 3C5H10) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7384 | Anti-TNFRSF6B Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC315 | Recombinant Anti-TNFRSF6B Eliminating Antibody, pH-Sensitive (VS-0625-YC315) | Antigen-Sweeping In Vivo. | Human IgG |
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