Because CD30 is highly expressed on Hodgkin's lymphoma and anaplastic large cell lymphoma, it is a promising target for immunotherapy. The extracellular portion of CD30 is cleaved, releasing a form known as soluble CD30 ("sCD30"), which can reduce the effects of CD30-targeting agents by competitive binding. The antibody binds to the membrane-specific epitopes (Ep7) are located near the middle of the extracellular domain of CD30 that are missing on soluble CD30. Ligands that bind to these epitopes can be used to target cells with intact CD30 without competition from sCD30.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-144 | Anti-Human CD30 Recombinant Antibody (Iratumumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-153 | Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (clone Brentuximab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G062E | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G062R | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-RTA | Cytotoxicity assay, Function study | |
AGTO-G062S | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-Sap | Cytotoxicity assay, Function study | |
AGTO-L041E | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L041R | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-635CL | Human Anti-TNFRSF8 Recombinant Antibody (TAB-635CL) | ELISA | Human IgG |
TAB-103LC | Anti-Human TNFRSF8 Recombinant Antibody | WB, FC, ELISA | Humanized antibody |
TAB-103LC-S(P) | Anti-Human TNFRSF8 Recombinant Antibody scFv Fragment | WB, FC, ELISA | Humanized antibody |
TAB-103LC-F(E) | Anti-Human TNFRSF8 Recombinant Antibody Fab Fragment | WB, FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC-1 | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0597MZ | Chicken Anti-TNFRSF8 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2165CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone mCD30.1) | FC, Stim, Costim, Block | Hamster IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2166CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone 2SH12-5F) | Neut, FC | Hamster IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3617 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3617AB) | WB, IHC-P | Rabbit IgG |
MOR-3618 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3618AB) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-YC-S(P) | Mouse Anti-TNFRSF8 Recombinant Antibody; scFv Fragment (HPAB-0329-YC-S(P)) | ELISA, FC, Cyt, FuncS | Mouse scFv |
HPAB-0250-FY-S(P) | Recombinant Human Anti-TNFRSF8 Antibody scFv Fragment | F, IH | Human scFv |
HPAB-1929-FY-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone 17G1); scFv Fragment | FC, ELISA | Human scFv |
HPAB-1931-FY-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone 5F11); scFv Fragment | FC, ELISA | Human scFv |
FAMAB-0358WJ-S(P) | Human Anti-TNFRSF8 Recombinant Antibody (clone AK30); scFv Fragment | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0445-CN-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T105); Fab Fragment | WB, ELISA, FC | Mouse Fab |
HPAB-0447-CN-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T405); Fab Fragment | WB, ELISA | Mouse Fab |
HPAB-0459-WJ-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0459-WJ-F(E)) | ELISA | Mouse Fab |
HPAB-1929-FY-S(P) | Human Anti-TNFRSF8 Recombinant Antibody (clone 17G1); Fab Fragment | FC, ELISA | Human Fab |
FAMAB-0358WJ-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone AK30); Fab Fragment | ELISA, WB | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0325CQ | Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0325CQ) | ELISA, FC, FuncS, Cyt | Humanized IgG |
HPAB-0326CQ | Mouse Anti-TNFRSF8 Recombinant Antibody (clone Ki-4) | WB, IP, ELISA | Mouse IgG1, κ |
HPAB-0459-WJ | Mouse Anti-TNFRSF8 Recombinant Antibody (HPAB-0459-WJ) | ELISA, FuncS | Mouse IgG |
FAMAB-1276CQ | Human Anti-TNFRSF8 Recombinant Antibody (clone Ki-3) | Activ, ELISA, FC, IF, IHC | Human IgG1 |
VS3-FY272 | Recombinant Mouse Anti-TNFRSF8 Antibody (clone 1B1A4G2) | ELISA, WB, ICC, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-144 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Iratumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-153 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Brentuximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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