What is the primary application of the UtomilumAb antibody?

The UtomilumAb antibody is primarily used in applications like ELISA and functional assays. These applications help researchers study the expression and functional involvement of the TNFRSF9 receptor in immune cell signaling and regulation.

What diseases are linked to the TNFRSF9 target that this antibody can help explore?

Research into cancer immunotherapy, including CAR-T cell therapy, often utilizes this antibody to target TNFRSF9, due to its potential to enhance antitumor immunity.

Human Anti-TNFRSF9 Recombinant Antibody (clone UtomilumAb)

CAT#: MOB-029LC

Recombinant fully human monoclonal antibody specifically binds to human 4-1BB

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg

RNA Expression Figure 2 RNA cell line category: Cell line enriched (HDLM-2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9

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Specifications

Host Species
Human

Type
Human IgG2

Specificity
Human TNFRSF9

Species Reactivity
Human

Clone
UtomilumAb

Applications
ELISA, FuncS

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
TNFRSF9; TNF receptor superfamily member 9; ILA; 4-1BB; CD137; CDw137

Gene ID
36044

UniProt ID
Q07011

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Breast cancer biomarkers at key points during disease progression

Perfect for Immune Signaling Studies

Using UtomilumAb, we've successfully mapped out critical pathways in immune signaling. Its reliable performance and high specificity have been instrumental in our experiments focusing on T-cell activation and function, yielding reproducible and insightful data.

Top Choice for Functional Assays

In our functional assays, UtomilumAb has consistently delivered high performance. Its ability to accurately engage with 4-1BB has allowed us to uncover new insights into T-cell regulation, significantly aiding our research into new immunotherapeutic targets.

Q&As

What is the primary application of the UtomilumAb antibody?

A: The UtomilumAb antibody is primarily used in applications like ELISA and functional assays. These applications help researchers study the expression and functional involvement of the TNFRSF9 receptor in immune cell signaling and regulation.
What diseases are linked to the TNFRSF9 target that this antibody can help explore?

A: Research into cancer immunotherapy, including CAR-T cell therapy, often utilizes this antibody to target TNFRSF9, due to its potential to enhance antitumor immunity.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-029LC.pdf

MSDS

MSDS - MOB-029LC.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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TAB-0613CLV-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0613CLV-F(E))	ELISA	Chimeric (mouse/human) Fab
TAB-0614CLV-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0614CLV-F(E))	ELISA	Chimeric (mouse/human) Fab
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HPAB-0809LY-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0809LY-F(E))	FC, FuncS	Human Fab
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HPAB-0812LY-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0812LY-F(E))	FC, FuncS	Human Fab
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