Rabbit Anti-TNFSF12 Recombinant Antibody (clone YC151); Fab Fragment (CAT#: PFBL-725)
Recombinant Rabbit Antibody Fab Fragment is specific to TNFSF12, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment could bind human TWEAK, neutralize TWEAK-Fn14 interaction and inhibit TWEAK-induced IL-8 secretion in A375 melanoma cells.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
Figure 3 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
Specifications
- Immunogen
- Human tumor necrosis factor (ligand) superfamily, member 12
- Host Species
- Rabbit
- Type
- Rabbit Fab
- Specificity
- Human TNFSF12
- Species Reactivity
- Human
- Clone
- YC151
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; APO3L; DR3LG; TWEAK; tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis
- Gene ID
- 8742
- UniProt ID
- O43508
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2051z | Mouse Anti-TNFSF12 Recombinant Antibody (clone 32B8) | FC, FuncS | Mouse IgG3 |
| PABL-354 | Human Anti-TNFSF12 Recombinant Antibody (clone YC155) | ELISA, Neut, FuncS | Human IgG |
| PABL-732 | Rabbit Anti-TNFSF12 Recombinant Antibody (clone YC150) | ELISA, Neut | Rabbit IgG |
| MOB-2131CT | Recombinant Mouse anti-Human TNFSF12 Monoclonal antibody (EML2038) | WB | |
| HPAB-1624-FY | Human Anti-TNFSF12 Recombinant Antibody (HPAB-1624-FY) | WB, ELISA, IF | Humanized IgG1 |
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