Human Anti-TNFSF12 Recombinant Antibody (clone YC155) (CAT#: PABL-354)
Recombinant Human Antibody is capable of binding to TWEAK, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TWEAK mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TWEAK mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
Figure 3 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
Specifications
- Immunogen
- Human tumor necrosis factor (ligand) superfamily, member 12
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human TNFSF12
- Species Reactivity
- Human
- Clone
- YC155
- Applications
- ELISA, Neut, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFSF12; tumor necrosis factor (ligand) superfamily; member 12; APO3L; DR3LG; TWEAK; tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis
- Gene ID
- 8742
- UniProt ID
- O43508
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-178 | Anti-Human TWEAK receptor Recombinant Antibody (TAB-178) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
| TAB-217CQ | Anti-Human TNFSF12 Recombinant Antibody (huP2D10-2) | ELISA, FC, Neut | Humanized antibody |
| TAB-217CQ-S(P) | Anti-Human TNFSF12 Recombinant Antibody scFv Fragment (huP2D10-2) | ELISA, FC, Neut | Humanized antibody |
| TAB-217CQ-F(E) | Anti-Human TNFSF12 Recombinant Antibody Fab Fragment (huP2D10-2) | ELISA, FC, Neut | Humanized antibody |
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