Human Anti-TSHR Recombinant Antibody (clone K1-70); scFv Fragment (CAT#: PSBL-730)

Recombinant Human Antibody (K1-70) scFv Fragment is specific to TSH receptor (TSHR), expressed in E. coli. The blocking autoantibody scFv fragment binds more N-terminally on the TSHR concave surface than either the stimulating autoantibody M22 or the hormone TSH, and this may reflect its different functional activity.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Human thyroid stimulating hormone receptor
  • Host Species
  • Human
  • Type
  • Human scFv
  • Specificity
  • Human TSHR
  • Species Reactivity
  • Human
  • Clone
  • K1-70
  • Applications
  • Block

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TSHR; thyroid stimulating hormone receptor; LGR3; CHNG1; hTSHR-I; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Recombinant Antibody scFv Fragment Antibody Fab Fragment Antibody Human Antibody Mouse Antibody Blocking Antibody
CAT Product Name Application Type
MOB-1074z Mouse Anti-TSHR Recombinant Antibody (clone 9B2) WB, ELISA, FC, IP, FuncS Mouse IgG1
PABW-172 Recombinant Human Anti-TSHR Antibody (M22) WB, ELISA, PK IgG
HPAB-0328CQ Mouse Anti-TSHR Recombinant Antibody (HPAB-0328CQ) ELISA, FC, Neut, FuncS Mouse IgG
HPAB-0329CQ Mouse Anti-TSHR Recombinant Antibody (HPAB-0329CQ) ELISA, FC, Neut, Agonist, FuncS Mouse IgG
HPAB-0367LY Human Anti-TSHR Recombinant Antibody (clone 5C9) Block, ELISA Human IgG1

Customer Reviews and Q&As

Customer Review Q&As

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  • Better specificity and affinity
    The Human Anti-TSHR Recombinant Antibody (clone K1-70); scFv Fragment has been a key component in our thyroid illness research. Its excellent specificity and affinity make our assays extremely trustworthy, while the smaller size of the scFv fragment improves tissue penetration for improved imaging.
  • Non-specific binding.
    The lack of cross-reactivity with other hormone receptors is a significant advantage of the K1-70 scFv Fragment. Our experiments have been free from the confounding variables often introduced by non-specific binding.
  • Effectiveness as an inhibitor
    Signal inhibition experiments using the K1-70 scFv Fragment have yielded new insights into TSHR signaling pathways. Its efficacy as an inhibitor makes it an invaluable tool in our research into thyroid-related illnesses.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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