Anti-Human VEGFA Recombinant Antibody scFv Fragment (TAB-009ML)
CAT#: TAB-009ML
Recombinant monoclonal antibody to VEGFA. It is a human monoclonal antibody that can be potentially used in the treatment of Age-related macular degeneration (AMD), neovascular (wet).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_7_5.jpg
Normal Tissue
Figure 2 Thyroid gland
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_1_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:
High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112715-VEGFA
❮
❯
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- scFv, κ
- Specificity
- Human VEGFA
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Inhibition
- Conjugate
- Unconjugated
- Related Disease
- Age-related macular degeneration (AMD), neovascular (wet)
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
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Versatile Research Tool
The scFv fragment's high specificity for VEGFA makes it an incredibly versatile tool in our angiogenesis studies. Its multiple application areas, from ELISA to flow cytometry, allow us to gain a comprehensive understanding of VEGFA dynamics in various biological systems.
Aiding in AMD Research
This scFv fragment has become a valuable resource in our age-related macular degeneration studies, offering insights into VEGFA's role in disease mechanisms and the potential development of targeted therapies.
Q&As
-
What is the primary target of the Anti-Human VEGFA Recombinant Antibody scFv Fragment?
A: This antibody specifically targets Vascular Endothelial Growth Factor A (VEGFA), a key protein involved in angiogenesis and vasculogenesis. It plays a critical role in the growth of blood vessels and is a vital marker for cancer research, especially in studies related to tumor angiogenesis and age-related macular degeneration (AMD).
-
What are the suitable research applications for this scFv fragment?
A: The Anti-Human VEGFA scFv Fragment is ideal for use in Enzyme-Linked Immunosorbent Assay (ELISA), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC), and inhibition studies. Its versatility supports a wide range of molecular and cellular biology research applications.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-009ML, RRID: AB_3111738)
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Biosimilar Overview
Please refer to Brolucizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Brolucizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "VEGFA"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H73 | Anti-Human VEGFA Recombinant Antibody (TAB-H73) | WB, FC, IP, ELISA, Neut, FuncS, IF | VH - C-kappa - CH2 - CH3 _ V-lambda - CH1 _ H-GAMMA-1 _ L-kappa |
| TAB-011 | Anti-Human VEGF Recombinant Antibody (Bevacizumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
| TAB-012-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-012-F(E)) | IP, IF, FuncS, FC, Neut, ELISA, IHC | Fab - G1 - kappa |
| TAB-307CQ | Human Anti-VEGFA Recombinant Antibody (TAB-307CQ) | Inhib | Human IgG |
| TAB-307CQ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-307CQ-S(P)) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L043L | anti-VEGFA immunotoxin Ng76 (scFv)-Luffin-β | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-131 | Human Anti-VEGFA Recombinant Antibody (clone bH1) | Inhib | Human IgG |
| PABW-131 | Human Anti-VEGFA Recombinant Antibody (clone YC159) | WB, ELISA | Human IgG |
| MRO-1578-CN | Rabbit Anti-VEGFA Recombinant Antibody (clone CBACN-578) | IF, IHC, IP, FC | Rabbit IgG |
| MRO-2269-CN | Rabbit Anti-VEGFA Polyclonal Antibody (MRO-2269-CN) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-M0372-YC | Canine Anti-VEGFA Recombinant Antibody (HPAB-M0372-YC) | FuncS, Inhib | Chimeric (Mouse/Canine) IgGB, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-131 | Human Anti-VEGFA Recombinant Antibody (clone bH1); Fab Fragment | WB, IF, FuncS | Human Fab |
| PFBW-131 | Human Anti-VEGFA Recombinant Antibody (clone YC159); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-0114-WJ-F(E) | Human Anti-VEGFA Recombinant Antibody (clone FD006); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0821-WJ-F(E) | Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-0821-WJ-F(E)) | ELISA | Mouse Fab |
| HPAB-0677YY-F(E) | Mouse Anti-VEGFA Recombinant Antibody (clone CBV110YJ); Fab Fragment | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-075 | Mouse Anti-VEGFA Recombinant Antibody (clone YADS1); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0151-FY-S(P) | Human Anti-VEGFA Recombinant Antibody (clone rhVVH); scFv Fragment | WB, ELISA, Inhib | Human scFv |
| HPAB-0671-CN-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0671-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0821-WJ-S(P) | Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0821-WJ-S(P)) | ELISA | Mouse scFv |
| HPAB-1245WJ-S(P) | Human Anti-VEGFA Recombinant Antibody (clone AM2); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-306CQ | Mouse Anti-VEGFA Recombinant Antibody (TAB-306CQ) | FuncS, Inhib | Mouse IgG |
| TAB-306CQ-S(P) | Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-306CQ-S(P)) | ELISA, Neut | Mouse scFv |
| TAB-306CQ-F(E) | Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-306CQ-F(E)) | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-284CQ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-284CQ-S(P)) | ELISA | Human scFv |
| TAB-284CQ-F(E) | Human Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-284CQ-F(E)) | ELISA | Human Fab |
| TAB-304CQ-F(E) | Anti-Human VEGFA Recombinant Antibody Fab Fragment (2H1) | ELISA, WB | Human antibody |
| TAB-305CQ-F(E) | Anti-Human VEGFA Recombinant Antibody Fab Fragment (2H1-32) | ELISA, WB | Human antibody |
| TAB-465CQ | Anti-Human VEGFA Recombinant Antibody (TAB-465CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0623MZ | Chicken Anti-VEGF Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2255CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL198) | Neut, WB | Mouse IgG1 |
| NEUT-2256CQ | Rat Anti-Vegfa Recombinant Antibody (clone 2G11-2A05) | WB, Neut, ELISA, IHC, FuncS | Rat IgG2a, κ |
| NEUT-2257CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 16F1) | WB, Neut | Mouse IgG2a |
| NEUT-2258CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 4B2-8) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-2260CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL737) | WB, ELISA, Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2259CQ | Mouse Anti-VEGFA Recombinant Antibody (clone A.4.6.1) | ELISA, IP, WB, Block, FC, IHC | Mouse IgG1, κ |
| NEUT-2267CQ | Mouse Anti-VEGFA Recombinant Antibody (NEUT-2267CQ) | WB, Block | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3835 | Rabbit Anti-VEGFA Recombinant Antibody (clone DS3835AB) | FC, ICC, IF, IHC-P, IP, WB | Rabbit IgG |
| MOR-4758 | Rabbit Anti-Vegfa Recombinant Antibody (clone TH272DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MD-ZBF-YC024 | Camelid Anti-VEGFA Recombinant Single Domain Antibody (MD-ZBF-YC024) | ELlSA | Camelid VHH |
| HPAB-0646-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0646-YJ-VHH) | ELISA, Inhib | Camelid VHH |
| HPAB-0647-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0647-YJ-VHH) | ELISA, Inhib | Camelid VHH |
| HPAB-0648-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0648-YJ-VHH) | ELISA, Inhib | Camelid VHH |
| HPAB-0656-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0656-YJ-VHH) | ELISA, WB, Inhib | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0151-FY | Human Anti-VEGFA Recombinant Antibody (clone rhVVH) | WB, ELISA, Inhib | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-465CQ | Afuco™ Anti-VEGFA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-465CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-011 | Afuco™ Anti-VEGFA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-011) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY273 | AbPlus™ Anti-VEGFA Magnetic Beads (A.4.6.1) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY540 | Mouse Anti-NHP VEGFA Recombinant Antibody (clone 26503) | WB, ELISA | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY46 | Human Anti-VEGFA (clone G6-31) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC709 | Recombinant Anti-VEGFA Vesicular Antibody, EV Displayed (VS-0425-YC709) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC190 | Recombinant Anti-VEGFA (N-terminus x C-terminus) Biparatopic Antibody, Tandem scFv (Clone C1039 x Clone c870) | ELISA | Tandem scFv |
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