Anti-Human folate receptor 1 Recombinant Antibody (TAB-113) (CAT#: TAB-113)
Recombinant monoclonal antibody to folate receptor 1. It is a monoclonal antibody which is being investigated for the treatment of ovarian cancer, It is targeted at FR-alpha which is overexpressed in some cancers such as ovarian cancer.
Specific Inquiry
WB
Figure 1 Anti-FOLR1 Antibody (TAB-113) in WB
Western blot analysis of TAB-113 was performed with Human FOLR1 Protein.
ELISA
Figure 2 Anti-FOLR1 Antibody (TAB-113) in ELISA
ELISA analysis of TAB-113 was performed by coating with Human FOLR1 Protein.
DB
Figure 3 Anti-FOLR1 Antibody (TAB-113) in Dot Blot
Dot Blot analysis of TAB-113 was performed by coating with Human FOLR1 Protein.
SDS-PAGE
Figure 4 Anti-Human folate receptor 1 Antibody (TAB-113) in SDS-PAGE
Lane 1: Non-reduced mAb
Lane 2: Reduced mAb
SEC-HPLC
Figure 5 Anti-Human folate receptor 1 Antibody (TAB-113) in SEC-HPLC
The purity of TAB-113 was greater than 95% as determined by SEC-HPLC.
Specifications
- Immunogen
- Gestational choriocarcinoma cell line, Lu-75.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF, ICC, PK, Cyt
- MW
- 145.4 kDa
- Related Disease
- Ovarian cancers
Product Property
- Purity
- >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The FOLR1 antibody has been reported in applications of FC, IP, ELISA, Neut, FuncS, IF, ICC, PK, Cyt.
Target
- Alternative Names
- Farletuzumab;896723-44-7;MORAb-003;LK26;MORAb-003;FOLR1;folate receptor 1 (adult);FOLR;folate receptor alpha;FR-alpha;KB cells FBP;folate binding protein;folate receptor, adult;adult folate-binding protein;ovarian tumor-associated antigen MOv18;FBP;
- Gene ID
- 2348
- UniProt ID
- P15328
Related Resources
Please refer to Farletuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Farletuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B029(A) | Recombinant Anti-human FOLR1 Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B029(G) | Recombinant Anti-human FOLR1 Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
| IAB-B029(T) | Recombinant Anti-human FOLR1 Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-113, RRID: AB_2941836)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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