BV421-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer
CAT#: MHC-LC050
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of BA46-derived peptide of GLQHWVPEL sequence covering 97-106 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_1_7_selected.jpg
Normal Tissue
Figure 3 IHC staining of human endometrium
High expression. RNA expression: 444.7 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_B_5_3_val_selected.jpg
Normal Tissue
Figure 4 IHC staining of human duodenum
Low expression. RNA expression: 21.2 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_9_2_val_selected.jpg
Normal Tissue
Figure 5 Cerebral cortex
Glial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8042_B_7_5.jpg
Normal Tissue
Figure 6 Colon
Enterocytes - Microvilli
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_3.jpg
Normal Tissue
Figure 7 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_8_4.jpg
Normal Tissue
Figure 8 Kidney
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (microvilli)
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_5.jpg
Normal Tissue
Figure 9 Testis
Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_4_6.jpg
Normal Tissue
Figure 10 Lymph node
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140545-MFGE8
❮
❯
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- BA46
- Antigen Species
- Human
- Peptide
- GLQHWVPEL
- Range
- 97-106
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
- Alternative Names
- MFGE8; milk fat globule-EGF factor 8 protein; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888
- Gene ID
- 911829
- UniProt ID
- Q05320
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| MOB-657-S(P) | Recombinant Anti-human MFGE8 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| MHH-657-S(P) | Recombinant Human Anti-human MFGE8 Antibody scFv Fragment | WB, IP, FuncS | scFv |
| FAMAB-0365JF-S(P) | Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); scFv Fragment | IB, WB, ELISA, FuncS | Mouse scFv |
| HPAB-2103-FY-S(P) | Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1); scFv Fragment | IA | Humanized scFv |
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| CAT | Product Name | Application | Type |
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| MHH-657 | Recombinant Human Anti-human MFGE8 Antibody | IF, ELISA, FuncS | IgG |
| MOB-1240MZ | Recombinant Mouse Anti-Human MFGE8 Antibody (clone FEN56), Biotin-Conjugated | ICC, IF, IHC-P, IP, WB | Mouse antibody |
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| HPAB-2104-FY | Mouse Anti-MFGE8 Recombinant Antibody (clone HMFG1) | IA | Mouse IgG |
| ZG-0144U | Mouse Anti-MFGE8 Recombinant Antibody (clone 2B2D10) | ELISA, IHC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0763CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0763CL-F(E)) | ELISA | Mouse Fab |
| TAB-0764CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0764CL-F(E)) | ELISA | Mouse Fab |
| TAB-0765CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0765CL-F(E)) | ELISA | Mouse Fab |
| TAB-0766CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0766CL-F(E)) | ELISA | Mouse Fab |
| TAB-0767CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0767CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0768CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0768CL-F(E)) | ELISA | Humanized Fab |
| TAB-0769CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0769CL-F(E)) | ELISA | Humanized Fab |
| TAB-0770CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0770CL-F(E)) | ELISA | Humanized Fab |
| TAB-0771CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0771CL-F(E)) | ELISA | Humanized Fab |
| TAB-0772CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0772CL-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC048 | PE-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer | FCM | |
| MHC-LC049 | APC-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer | FCM | |
| MHC-YF323 | A*02:01/Human BA46 (NLFETPVEA) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0365JF | Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10) | WB, ELISA, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4370 | Anti-MFGE8 Immunohistochemistry Kit | IHC |
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