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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    BV421-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer (CAT#: MHC-LC050)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of BA46-derived peptide of GLQHWVPEL sequence covering 97-106 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

    Specific Inquiry
    • Size:
    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/if_selected.jpg
    Figure 2 IHC staining of human placenta
    Figure 2 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_1_7_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human endometrium
    Figure 3 IHC staining of human endometrium
    (High expression. RNA expression: 444.7 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_B_5_3_val_selected.jpg
    Figure 4 IHC staining of human duodenum
    Figure 4 IHC staining of human duodenum
    (Low expression. RNA expression: 21.2 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_9_2_val_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Glial cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8042_B_7_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Enterocytes - Microvilli
    Staining: High
    Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_8_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Collecting ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Distal tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Proximal tubules (microvilli)
    Staining: High
    Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Cells in seminiferous ducts
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_4_6.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Non-germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
    Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140545-MFGE8

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • BA46
    • Antigen Species
    • Human
    • Peptide
    • GLQHWVPEL
    • Range
    • 97-106
    • Conjugate
    • BV421
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
    • Alternative Names
    • MFGE8; milk fat globule-EGF factor 8 protein; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "MFGE8"

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    CAT Product Name Application Type
    MOB-657 Recombinant Anti-human MFGE8 Antibody WB, Neut, FuncS IgG
    MHH-657 Recombinant Human Anti-human MFGE8 Antibody IF, ELISA, FuncS IgG
    MOB-1240MZ Recombinant Mouse Anti-Human MFGE8 Antibody (clone FEN56), Biotin-Conjugated ICC/IF, IHC-P, IP, WB Mouse antibody
    HPAB-2103-FY Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1) IA Human IgG1
    ZG-0144U Mouse Anti-MFGE8 Recombinant Antibody (clone 2B2D10) ELISA, IHC Mouse IgG2b

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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