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    BV421-B-FIV21/Gallus gallus TUBB1 (REVDEQLLSV) MHC Tetramer (CAT#: MHC-LC1384)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of TUBB1-derived peptide of REVDEQLLSV covering 324-333 and B-FIV21 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
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    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human placenta
    Figure 1 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4286/ihc_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_A_7_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_A_8_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_A_6_6.jpg
    Figure 6 Fallopian tube
    Figure 6 Fallopian tube
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_A_7_7.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/46280/103953_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enriched (HEL)
    Figure 8 RNA cell line category: Cell line enriched (HEL)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101162-TUBB1

    Specifications

    • Allele
    • B-FIV21
    • Class
    • Class I
    • MHC Species
    • Chicken
    • Antigen
    • Tubulin
    • Antigen Species
    • Gallus gallus
    • Peptide
    • REVDEQLLSV
    • Range
    • 324-333
    • Conjugate
    • BV421
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia.
    • Alternative Names
    • TUBB1; tubulin beta 1 class VI

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    Please select product type
    MHC Tetramer Products for Other Applications IgG Antibody Products Non-Human Primate (NHP) Antibody Products
    CAT Product Name Application Type
    MHC-LC1382 PE-B-FIV21/Gallus gallus TUBB1 (REVDEQLLSV) MHC Tetramer FCM
    MHC-LC1383 APC-B-FIV21/Gallus gallus TUBB1 (REVDEQLLSV) MHC Tetramer FCM

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