BV421-B-FIV21/Gallus gallus YWHAQ (TNPESKVFYL) MHC Tetramer (CAT#: MHC-LC1702)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of YWHAQ-derived peptide of TNPESKVFYL covering 110-119 and B-FIV21 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • B-FIV21
  • Class
  • Class I
  • MHC Species
  • Chicken
  • Antigen
  • YWHAQ
  • Antigen Species
  • Gallus gallus
  • Peptide
  • TNPESKVFYL
  • Range
  • 110-119
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
  • Alternative Names
  • YWHAQ; tyrosine 3-monooxygenase; tryptophan 5-monooxygenase activation protein theta

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