Benralizumab (CAT#: Gly-006CL)
Benralizumab (INN) is a monoclonal antibody which is being developed by MedImmune for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).
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RNA Expression
Figure 1 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091181-IL5RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091181-IL5RA
Specifications
- Type
- Humanized (from mouse) Whole antibody
- Protein chemical formula
- C6492H10060N1724O2028S42
- Protein average weight
- 146.0 kg/mol
- CAS number
- 1044511-01-4
- Class
- Antiasthmatics; Monoclonal antibodies
- Mechanism of action
- Interleukin 5 receptor antagonists
References
- Synonyms
- MEDI-563 (BIW-8405); Anti-IL-5Rα Mab; Anti-IL5Ra monoclonal antibody; Anti-interleukin-5 receptor alpha monoclonal antibody; BIW-8405-IL-5R; KHK 4563;
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Recombinant Antibody
| CAT | Product Name | Application | Type |
| MOB-2473z | Mouse Anti-IL5RA Recombinant Antibody (clone 33H12) | WB, FC | Mouse IgG1 |
| HPAB-1545WJ | Human Anti-IL5RA Recombinant Antibody (clone KM1399) | ELISA, WB | Human IgG1, κ |
Humanized Antibody
| CAT | Product Name | Application | Type |
| TAB-222 | Anti-Human IL5RA Recombinant Antibody (Benralizumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG1 - kappa |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
| MOR-1813 | Rabbit Anti-IL5RA Recombinant Antibody (clone DS1813AB) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
| AFC-TAB-222 | Afuco™ Anti-IL5RA ADCC Recombinant Antibody (Benralizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-1545WJ-F(E) | Human Anti-IL5RA Recombinant Antibody; Fab Fragment (clone KM1399) | ELISA, WB | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-1545WJ-S(P) | Human Anti-IL5RA Recombinant Antibody; scFv Fragment (clone KM1399) | ELISA, WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
WBWestern Blot
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