Products

Anti-CD15 × Anti-FcγRI Bispecific Antibody (FAB-L029)

Recombinant Anti-CD15 × Anti-FcγRI Bispecific Antibody (F(ab`)2) is a chemical conjugate composed of the Fab' of the anti-CD15 monoclonal antibody and Fab' of an antibody specific for FcγRI. A stable thioether linkage is formed between the two Fab'. This BsAb can retarget of neutrophils to tumor cells. It was designed for the treatment of promyelocytic leukemia.      

Specifications
Targets
CD15 & FcγRI
Type
F(ab')2
Species Reactivity
Human
Target 1
CD15
Host
Mouse
Target 2
FcγRI
Host
Mouse
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Promyelocytic leukemia
Targets
Target 1
CD15
Gene ID
2526
UniProt ID
P22083
Alternative Names
FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1
Target 2
FcγRI
Gene ID
2209
UniProt ID
P12314
Alternative Names
CD64; FCRI; CD64A; IGFR1

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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