Products

Anti-CD40 × Anti-Ad fiber knob Bispecific Antibody (TAND-L063)

Recombinant Anti-CD40 × Anti-Ad fiber knob Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.      

Specifications
Targets
CD40 & Ad fiber knob
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
CD40
Host
Mouse
Clone
G28-5
Target 2
Ad fiber knob
Host
Mouse
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Gene delivery in gene therapy
Related Disease
Acute myeloid leukaemic (AML)
Targets
Target 1
CD40
Gene ID
958
UniProt ID
P25942
Alternative Names
p50; Bp50; CDW40; TNFRSF5
Target 2
Ad fiber knob

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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