Products

Anti-CD8 × Anti-CD3 Bispecific Antibody (FAB-L065)

Recombinant Anti-CD8 × Anti-CD3 Bispecific Antibody (F(ab')2) is a chemical conjugate composed of the Fab' of the anti-CD8 monoclonal antibody and Fab' of an antibody specific for CD3. A stable thioether linkage is formed between the two Fab'. This BsAb is capable of targeting the tumor and recruiting T effector cells via binding to the CD3 subunit of the T cell receptor complex. It was designed for the treatment of ADIS.      

Specifications
Targets
CD8 & CD3
Type
F(ab')2
Species Reactivity
Mouse
Target 1
CD8
Host
Mouse
Target 2
CD3
Host
Mouse
Clone
--
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
ADIS
Targets
Target 1
CD8
Gene ID
12525
UniProt ID
P01731
Alternative Names
CD8; MAL; p32; Leu2
Target 2
CD3
Gene ID
12501
UniProt ID
A6H6M1
Alternative Names
CD3; Cd3e; CD3 antigen, epsilon polypeptide; T3e; AI504783; CD3epsilon

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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