Products

Anti-CEA × Anti-Ad fiber knob Bispecific Antibody (TAND-L062)

Recombinant Anti-CEA × Anti- Ad fiber knob(TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb can retarget of adenoviral vectors to tumour cells.It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.      

Specifications
Targets
CEA & Ad fiber knob
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
CEA
Host
Mouse
Clone
35A7
Target 2
Ad fiber knob
Host
Mouse
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Gene delivery in gene therapy
Related Disease
CEA-expressing tumors
Targets
Target 1
CEA
Gene ID
1048
UniProt ID
A0A024R0K5
Alternative Names
CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
Ad fiber knob

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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