Recombinant Anti-CLEC12A × Anti-CD3 Bispecific Antibody (CrossMab) (CAT#: CROSS-L002)
Recombinant Anti-CLEC12A × Anti-CD3 Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb is capable of targeting the tumor and recruiting T effector cells via binding to the CD3 subunit of the T cell receptor complex. It was designed for the treatment of myelodysplastic syndrome (MDS), chronic myelogenous leukemia (CML) or acute myeloid leukemia (AML).
Specific Inquiry
Specifications
- Target
- CLEC12A & CD3
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- CLEC12A
- Host Species 1
- Mouse
- Target 2
- CD3
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Myelodysplastic syndrome (MDS), Chronic myelogenous leukemia (CML) or Acute myeloid leukemia (AML)
Target
- Target 1
- CLEC12A
- Gene ID
- 160364
- UniProt ID
- Q5QGZ9
- Alternative Names
- CLEC12A; C-type lectin domain family 12, member A; CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like re
- Target 2
- CD3
- Gene ID
- 916
- UniProt ID
- P07766
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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F(ab')₂ Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAB-L010 | Recombinant Anti-CLEC12A × Anti-CD3 Bispecific Antibody (Fab2) | FuncS, Promising therapeutic agent | Fab2 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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