Recombinant Anti-CLEC12A × Anti-CD3 Bispecific Antibody (Fab2) (CAT#: FAB-L010)
Recombinant Anti-CLEC12A & Anti-CD3 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CLEC12A monoclonal antibody and Fab of an antibody specific for CD3. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it can be cleared from the blood naturally at a faster rate. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of CLEC12A-positive AML.
Specific Inquiry
Specifications
- Target
- CLEC12A & CD3
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CLEC12A
- Host Species 1
- Human
- Target 2
- CD3
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- CLEC12A-positive AML tumor
Target
- Target 1
- CLEC12A
- Gene ID
- 160364
- UniProt ID
- Q5QGZ9
- Alternative Names
- CLEC12A; C-type lectin domain family 12, member A; CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like re
- Target 2
- CD3
- Gene ID
- 916
- UniProt ID
- P07766
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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CrossMab
| CAT | Product Name | Application | Type |
|---|---|---|---|
| CROSS-L002 | Recombinant Anti-CLEC12A × Anti-CD3 Bispecific Antibody (CrossMab) | FuncS, Promising therapeutic agent | CrossMab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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