Products

Anti-DKKl × Anti-SOST Bispecific Antibody (TAND-L037)

Recombinant Anti-DKKl × Anti-SOST Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. TandAbs do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than BiTEs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with BiTEs.      

Specifications
Targets
DKKl & SOST
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
DKKl
Host
Human
Target 2
SOST
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Targets
Target 1
DKKl
Gene ID
27120
UniProt ID
Q9UK85
Alternative Names
DKKL1; dickkopf-like 1; SGY; CT34; SGY1; SGY-1; dickkopf-like protein 1; soggy
Target 2
SOST
Gene ID
50964
UniProt ID
Q9BQB4
Alternative Names
SOST; sclerostin; CDD; VBCH; SOST1

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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