Recombinant Anti-DLL4 × Anti-VEGF Bispecific Antibody (Bi-sdAb, A1)
CAT#: NANO-MZ001
This bispecific binding molecule is useful as pharmacologically active agents in compositions in the prevention, treatment, alleviation and diagnosis of diseases or conditions that can be modulated by inhibition of DII4, such as cancer. It is also capable of blocking DLL4 and VEGF activation as well as inhibiting the VEGF induced Erk phosphoryaltion.
Specifications
- Target
- DLL4 & VEGF
- Type
- Bi-sdAb
- Species Reactivity
- Human
- Target 1
- DLL4 (Delta like ligand 4)
- Host Species 1
- Llama
- Target 2
- VEGF
- Host Species 2
- Llama
- Application
- ELISA
- Related Disease
- Human colon cancer
Target
- Target 1
- DLL4 (Delta like ligand 4)
- Gene ID
- 54567
- UniProt ID
- Q9NR61
- Alternative Names
- DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
- Target 2
- VEGF
- Alternative Names
- VEGF; Vascular endothelial growth factor
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