Recombinant Anti-DR5 × Anti-FAP Bispecific Antibody (Fab2) (CAT#: FAB-L013)

Recombinant Anti-DR5 & Anti-FAP Bispecific Antibody (Fab2) is composed of the Fab of the anti-DR5 monoclonal antibody and Fab of an antibody specific for FAP. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG, and therefore it can be cleared from the blood naturally at a faster rate. It was designed for the treatment of lung carcinomas, colorectal carcinomas, bladder carcinomas, ovarian carcinomas and breast carcinomas.


Specific Inquiry
  • Size:
  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • DR5 & FAP
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • DR5
  • Host Species 1
  • Human
  • Target 2
  • FAP
  • Host Species 2
  • Human
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Lung carcinomas, colorectal carcinomas, bladder carcinomas, ovarian carcinomas, breast carcinomas

Target

  • Target 1
  • DR5
  • Alternative Names
  • DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10b; TNFRSF10B
  • Target 2
  • FAP
  • Alternative Names
  • FAP; fibroblast activation protein, alpha; FAPA; SIMP; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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