Products

Anti-FcγRI × Anti-GD2 Bispecific Antibody (FAB-L039)

Recombinant Anti-FcγRI × Anti-GD2 Bispecific Antibody (F(ab')2) is a chemical conjugate composed of the Fab' of the anti-FcγRI monoclonal antibody and Fab' of an antibody specific for GD2. A stable thioether linkage is formed between the two Fab'. This BsAb can retarget of neutrophils to tumor cells. It was designed for the treatment of Neuroblastoma
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Specifications
Targets
FcγRI & GD2
Type
F(ab')2
Target 1
FcγRI
Host
Mouse
Clone
22
Target 2
GD2
Host
Mouse
Clone
7A4
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Neuroblastoma
Targets
Target 1
FcγRI
Gene ID
2209
UniProt ID
P12314
Alternative Names
CD64; FCRI; CD64A; IGFR1
Target 2
GD2
Alternative Names
GD2; Disialoganglioside

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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