Recombinant Anti-HER2 × Anti-MET Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L007)

Recombinant Anti-HER2 × Anti-c-Met Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. Tandem Diabodies do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs, but larger than tandem scFvs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with tandem scFvs. This BsAb can simultaneously block two receptors. It was designed for the treatment of numerous cancers, including prostate tumor, bladder tumor, and breast tumor,kidney cancer, liver cancer, stomach cancer, breast cancer and brain cancer.


Specific Inquiry
  • Size:
  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • HER2 & MET
  • Type
  • Tandem Diabody
  • Species Reactivity
  • Human
  • Target 1
  • HER2
  • Host Species 1
  • Human
  • Target 2
  • MET
  • Host Species 2
  • Human
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Numerous cancers, including prostate tumors, bladder tumors, and breast tumors,kidney cancers, liver cancers, stomach cancers, breast cancers, brain cancers

Target

  • Target 1
  • HER2
  • Alternative Names
  • ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 1
  • Target 2
  • MET
  • Alternative Names
  • MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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