Recombinant Anti-HER3 × Anti-ErbB-2 Bispecific Antibody (Bi-sdAb)
CAT#: NANO-MZ002
This bispecific antibody is composed of two single domain antibodies targeting HER3 and HER2/neu, respectively. It is capable of mediating a reduction in the quantity of HER2/neu and HER3 on the surface of tumor cells, which is a similar mechanism to internalization.
Specifications
- Target
- HER3 & ErbB-2
- Type
- Bi-sdAb
- Species Reactivity
- Human
- Target 1
- HER3
- Host Species 1
- Human
- Target 2
- ErbB-2
- Host Species 2
- Human
- Application
- PET-CT imaging
- Related Disease
- Breast cancer
Target
- Target 1
- HER3
- Gene ID
- 2065
- UniProt ID
- P21860
- Alternative Names
- ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
- Target 2
- ErbB-2
- Gene ID
- 2064
- UniProt ID
- P04626
- Alternative Names
- ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;
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