Recombinant Anti-HER3 × Anti-ErbB-2 Bispecific Antibody (Bi-sdAb) (CAT#: NANO-MZ002)
This bispecific antibody is composed of two single domain antibodies targeting HER3 and HER2/neu, respectively. It is capable of mediating a reduction in the quantity of HER2/neu and HER3 on the surface of tumor cells, which is a similar mechanism to internalization.
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Specifications
- Target
- HER3 & ErbB-2
- Type
- Bi-sdAb
- Species Reactivity
- Human
- Target 1
- HER3
- Host Species 1
- Human
- Target 2
- ErbB-2
- Host Species 2
- Human
- Application
- PET-CT imaging
- Related Disease
- Breast cancer
Target
- Target 1
- HER3
- Gene ID
- 2065
- UniProt ID
- P21860
- Alternative Names
- ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
- Target 2
- ErbB-2
- Gene ID
- 2064
- UniProt ID
- P04626
- Alternative Names
- ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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