Recombinant Anti-IL4 × Anti-IL13 Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L033)

Recombinant Anti-IL4 × Anti-IL13 Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. Tandem Diabodies do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than tandem scFvs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with tandem scFvs. This BsAb is capable of inhibiting signaling of their cognate cytokines and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of allergic asthma and dermatitis.


Specific Inquiry
  • Size:
  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • IL4 & IL13
  • Type
  • Tandem Diabody
  • Species Reactivity
  • Human
  • Target 1
  • IL4
  • Host Species 1
  • Human
  • Target 2
  • IL13
  • Host Species 2
  • Human
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Allergic asthma and Dermatitis

Target

  • Target 1
  • IL4
  • Alternative Names
  • IL4; interleukin 4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; interleukin 4 variant 2; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1
  • Target 2
  • IL13
  • Alternative Names
  • IL13; interleukin 13; P600; IL-13; interleukin-13

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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