Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L050)
Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb is capable of targeting the tumor and recruiting T effector cells via binding to the CD3 subunit of the T cell receptor complex. It was designed for the treatment of Ovarian cancer .
Specific Inquiry
Specifications
- Target
- PLAP & CD3
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- PLAP
- Host Species 1
- Mouse
- Target 2
- CD3
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Ovarian cancer
Target
- Target 1
- PLAP
- Gene ID
- 250
- UniProt ID
- P05187
- Alternative Names
- ALPP; alkaline phosphatase, placental; ALP; PALP; PLAP; PLAP-1; alkaline phosphatase, placental type; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme
- Target 2
- CD3
- Gene ID
- 916
- UniProt ID
- P07766
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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F(ab')₂ Products
CrossMab Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAB-L020 | Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (Fab2) | FuncS, Promising therapeutic agent | Fab2 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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