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  • Anti-Canine MS4A1 Recombinant Antibody (TAB-007ML)

Anti-Canine MS4A1 Recombinant Antibody (TAB-007ML) (CAT#: TAB-007ML)

Recombinant monoclonal antibody to MS4A1. It is a caninized monoclonal antibody that can be potentially used in the treatment of Canine B-cell lymphoma.

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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg
Figure 5 Bone marrow
Figure 5 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Canine
  • Derivation
  • Caninized
  • Type
  • IgG2, κ, λ
  • Specificity
  • Canine MS4A1
  • Species Reactivity
  • Canine
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
  • Conjugate
  • Unconjugated
  • Related Disease
  • Canine B-cell lymphoma

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • Membrane-spanning 4-domains subfamily A member 1; CD20

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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CAT Product Name Application Type
TAB-017 Anti-Human CD20 Recombinant Antibody (TAB-017) Neut, ELISA, IF, IP, FuncS, FC, ICC IgG2a - lambda
TAB-711 Anti-MS4A1 Recombinant Antibody (Technetium (99MTC) Nofetumomab Merpentan) FC, IP, ELISA, Neut, FuncS, IF, ICC Fab - G2b - kappa
TAB-001 Anti-Human CD20 Recombinant Antibody (Ibritumomab) ELISA, IP, FC, FuncS, IF, Neut IgG1 - kappa
TAB-H27 Anti-Human MS4A1 Recombinant Antibody (Epitumomab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG2a
TAB-H39 Anti-Human MS4A1 Recombinant Antibody (Ibritumomab) FC, IP, ELISA, Neut, FuncS, IF, ICC Mouse IgG1 - kappa

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Superior Performance in Flow Cytometry
We have found this antibody to excel in flow cytometry applications. It delivers high-resolution results and clean separation of B-cell populations without non-specific staining, crucial for our immuno-phenotyping protocols.

Versatility in Applications
Its broad application spectrum-from ELISA to functional studies-demonstrates the antibody's adaptability in various experimental contexts, allowing us a comprehensive approach in our canine immunological studies.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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