Botulinum Toxin Type B (CAT#: TP-065CL)
Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
Specifications
- Classify
- Protein therapeutics providing a novel function or activity: Enzymatic degradation of macromolecules
- Therapeutic
- Botulinum toxin type B
- Trade Name
- Myoblock
- Function
- Cleaves synaptobrevin at neuromuscular junctions to disrupt sNAre complex and prevent acetylcholine release, causing flaccid paralysis
- Examples of clinical use
- Many types of dystonia, particularly cervical; cosmetic uses
References
- Synonyms
- Botulinum neurotoxin type B precursor, BTX-B, RimabotulinumtoxinB
- UniProt
- P10844
- Genbank
- M81186
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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