Coagulation factor VIIa Recombinant Human (CAT#: TP-051CL)
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4826/1763_A4_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4826/1763_A4_1_selected.jpg
Figure 2 RNA cell line category: Group enriched (CACO-2, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000057593-F7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000057593-F7
Specifications
- Classify
- Protein therapeutics augmenting an existing pathway: Haemostasis and thrombosis
- Therapeutic
- Factor VIIa
- Trade Name
- Novoseven
- Function
- Pro-thrombotic (activated factor vii; initiates the coagulation cascade)
- Examples of clinical use
- Haemorrhage in patients with haemophilia A or B and inhibitors to factor viii or factor iX
References
- Synonyms
- Coagulation factor VIIa, Coagulation factor VIIa (recombinant), Eptacog alfa, Eptacog alfa (activated), rFVIIa
- UniProt
- P08709
- Genbank
- M13232
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1409z | Mouse Anti-F7 Recombinant Antibody (clone 36D2) | ELISA, WB | Mouse IgG1 |
| MOB-0375MZ | Recombinant Mouse Anti-Human Factor VII Antibody (clone BIWIII-5032) | RIA, WB, ELISA | Mouse antibody |
| MOB-1612MZ | Recombinant Mouse Anti-Human F7 Antibody | ELISA, RIA, WB | Mouse antibody |
| FAMAB-1094CQ | Human Anti-F7 Recombinant Antibody (clone RFF-VII/1) | RIA, Block | Human IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1228 | Hi-Affi™ Rabbit Anti-F7 Recombinant Antibody (clone DS1228AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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