Anti-Human SELP Recombinant Antibody (Crizanlizumab) (CAT#: TAB-015ML)
Recombinant monoclonal antibody to SELP. Crizanlizumab is a human monoclonal antibody that can be potentially used in the treatment of Sickle Cell Disease (SCD).
Specific Inquiry
ELISA
Figure 1 Anti-Human SELP Protein Antibody in ELISA
ELISA analysis of TAB-015ML was performed by coating with Recombinant Human SELP Protein. Then blocked with BSA, and incubated with TAB-015ML. The HRP-conjugated goat anti-human IgG as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
SDS-PAGE
Figure 2 Anti-Human SELP Recombinant Antibody (TAB-015ML) in SDS-PAGE
SDS-PAGE analysis of TAB-015ML in non-reduced (Lane 1) and β-mercaptoethanol-reduced (Lane 2) conditions.
SEC-HPLC
Figure 3 Anti-Human SELP Recombinant Antibody (TAB-015ML) in HPLC
The purity of TAB-015ML was greater than 98% as determined by SEC-HPLC.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- IgG2, κ
- Specificity
- Human SELP
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
- Conjugate
- Unconjugated
- CAS
- 1690318-25-2
- Generic Name
- Crizanlizumab
- UNII
- L7451S9126
- Related Disease
- Sickle Cell Disease (SCD)
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
Related Resources
Please refer to Crizanlizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Crizanlizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Crizanlizumab"
Afuco™ Anti-SELP ADCC Recombinant Antibody (Crizanlizumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to SELP. Crizanlizumab is a human monoclonal antibody that can be potentially used in the treatment of Sickle Cell Disease (SCD).
See other products for "SELP"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-246 | Anti-Human selectin P Recombinant Antibody (Inclacumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-263CT | Mouse Anti-SELP Recombinant Antibody (TAB-263CT) | Inhib, FC | Mouse IgG |
| TAB-263CT-S(P) | Mouse Anti-SELP Recombinant Antibody; scFv Fragment (TAB-263CT-S(P)) | WB, ELISA | Mouse scFv |
| TAB-263CT-F(E) | Mouse Anti-SELP Recombinant Antibody; Fab Fragment (TAB-263CT-F(E)) | WB, ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-264CT | Humanized Anti-SELP Recombinant Antibody (TAB-264CT) | WB, ELISA | Humanized antibody |
| TAB-264CT-S(P) | Humanized Anti-SELP Recombinant Antibody; scFv Fragment (TAB-264CT-S(P)) | WB, ELISA | Humanized scFv |
| TAB-264CT-F(E) | Humanized Anti-SELP Recombinant Antibody; Fab Fragment (TAB-264CT-F(E)) | WB, ELISA | Humanized Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1933CQ | Recombinant Mouse Anti-SELP Antibody (AK4) | WB, IP, FuncS, ICC, FC, BL | IgG1 |
| NEUT-1934CQ | Recombinant Mouse Anti-Selp Antibody (RMP-1) | FC, IF, IHC, ELISA, WB, IP, BL | IgG2a, κ |
| NEUT-1936CQ | Recombinant Mouse Anti-SELP Antibody (VMC207) | BL, IHC | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1935CQ | Recombinant Mouse Anti-Selp Antibody (Psel.KO2.12) | FC, FuncS, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3203 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (DS3203AB) | WB, IHC-P | IgG |
| MOR-4550 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (TH60DS) | WB, IF, ICC, FC, ELISA | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0257-YC-F(E) | Mouse Anti-SELP Recombinant Antibody (clone 5C7.29); Fab Fragment | FC, Block | Mouse Fab |
| HPAB-0258-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone hu5C7.29); Fab Fragment | FC, Block | Humanized Fab |
| HPAB-0259-YC-F(E) | Mouse Anti-SELP Recombinant Antibody (clone PB1.3); Fab Fragment | ELISA, Block | Mouse Fab |
| HPAB-0260-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone huPB1.3); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0041-YJ-F(E) | Human Anti-SELP Recombinant Antibody (clone CY1748); Fab Fragment | RIA, ELISA, Block | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-015ML | Afuco™ Anti-SELP ADCC Recombinant Antibody (Crizanlizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-246 | Afuco™ Anti-SELP ADCC Recombinant Antibody (Inclacumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP436-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 005); scFv Fragment | ELISA | Human scFv |
| HPAB-AP437-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 010I); scFv Fragment | ELISA | Human scFv |
| HPAB-AP438-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 011); scFv Fragment | ELISA | Human scFv |
| HPAB-AP439-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 017); scFv Fragment | ELISA | Human scFv |
| HPAB-J0222-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone AP023/YC); scFv Fragment | ELISA, WB, FuncS | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0222-YC | Human Anti-SELP Recombinant Antibody (clone AP023/YC) | ELISA, WB, FuncS | Human IgG |
| VS3-CJ690 | Mouse Anti-SELP Recombinant Antibody (clone WAPS12.2) | IF, FC | Mouse IgG1 |
| VS3-XY1405 | Mouse Anti-SELP Recombinant Antibody, FITC (clone 4AWAPS12.2) | FC, IF | Mouse IgG1 |
| VS3-XY1406 | Mouse Anti-SELP Recombinant Antibody, PE (clone 4AWAPS12.2) | FC, IF | Mouse IgG1 |
| VS3-XY1407 | Mouse Anti-SELP Recombinant Antibody (clone 4AWAPS12.2) | FC, IF | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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