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Cystine knot scaffold protein anti-Bovine BSA (CAT#: SCK-L070)

The Cystine knot that bound BSA was isolated from the library using Phage display techonology. After affinity maturation, Cystine knot variants were identified having affinities for BSA as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


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  • Datasheet
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  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line Hep G2
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to endoplasmic reticulum & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/763_G10_1_selected.jpg
Figure 2 IHC staining of human fallopian tube
Figure 2 IHC staining of human fallopian tube
(Immunohistochemical staining of human fallopian tube shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6262/17728_A_9_7_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_7_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining:Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_7_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31024/128566_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (Hep G2)
Figure 7 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163631-ALB

Specifications

  • Scaffold Name
  • Cystine knot
  • Origin
  • Cytochrome b-562
  • Core Structure
  • 4-α helixes
  • Variable Regions
  • 2 Loops
  • Target
  • BSA
  • Species Reactivity
  • Bovine
  • Expression Host
  • E. coli
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • Cytochrome b-562; Cystine knot; ALB; bovine serum albumin; BSA

Downloads

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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