E*01:03/Human HLA-A leader 3-11 (VMAPRTLVL) MHC Tetramer (CAT#: MHC-LC594)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HLA-A leader 3-11-derived peptide of VMAPRTLVL sequence covering 3-11 and HLA-E*01:03 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • E*01:03
  • Class
  • Class I
  • Antigen
  • HLA-A leader 3-11
  • Antigen Species
  • Human
  • Peptide
  • VMAPRTLVL
  • Range
  • 3-11
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
  • Alternative Names
  • HLA-A; Major histocompatibility complex, class I, A; HLAA

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HLA-A"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-500-F(E) Recombinant Anti-human HLA-A Antibody Fab Fragment Neut, IF, FuncS Fab
MHH-500-F(E) Recombinant Human Anti-human HLA-A Antibody Fab Fragment WB, IF, FuncS Fab
PFBC-072 Human Anti-HLA-A Recombinant Antibody (clone HYB3); Fab Fragment WB, ELISA Human Fab
HPAB-1096WJ-F(E) Mouse Anti-HLA-A Recombinant Antibody; Fab Fragment (HPAB-1096WJ-F(E)) ELISA Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-500-S(P) Recombinant Anti-human HLA-A Antibody scFv Fragment ELISA, WB, IF, FuncS scFv
MHH-500-S(P) Recombinant Human Anti-human HLA-A Antibody scFv Fragment ELISA, WB, FuncS scFv
PSBC-072 Human Anti-HLA-A Recombinant Antibody (clone HYB3); scFv Fragment WB, ELISA Human scFv
HPAB-1096WJ-S(P) Mouse Anti-HLA-A Recombinant Antibody; scFv Fragment (HPAB-1096WJ-S(P)) ELISA Mouse scFv

Recombinant Antibody

CAT Product Name Application Type
MHH-500 Recombinant Human Anti-human HLA-A Antibody ELISA, IP, FuncS IgG
PABC-072 Human Anti-HLA-A Recombinant Antibody (clone HYB3) WB, ELISA, IF, FC Human IgG
MOB-2307MZ Recombinant Mouse Anti-Human HLA-A Antibody (clone 9.M.208), Biotin-Conjugated FC, ICC/IF Mouse antibody
MRO-0996-CN Rabbit Anti-HLA-A Recombinant Antibody (clone JF10-38) WB, IF, IHC, FC Rabbit IgG
ZG-1014F Mouse Anti-HLA-A Antibody (clone BRA-23/9) FC, IHC-Fr Mouse IgG2a

Immunotoxin

CAT Product Name Application Type
AGTO-L022F anti-HLA-A immunotoxin Fib75 (IgG)-α-sar Cytotoxicity assay, Functional assay

Human Antibody

CAT Product Name Application Type
PABX-105 Recombinant Human Anti-HLA-A Antibody (T1) WB, ELISA, FuncS IgG
PABX-105-S (P) Recombinant Human Anti-HLA-A Antibody scFv Fragment (T1) WB, ELISA, FuncS scFv

MHC Tetramer for Other Applications

CAT Product Name Application Type
MHC-LC595 E*01:01/Human HLA-A leader 3-11 (VMAPRTLVL) MHC Tetramer FCM
MHC-LC646 E*01:03/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer FCM
MHC-LC647 E*01:01/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer FCM
MHC-LC664 E*01:03/Human HLA-A*02, A*24 leader (VMAPRTLVL) MHC Tetramer FCM
MHC-YF184 HLA-E*01:01/Human HLA-A (VMAPRTLVL) MHC Monomer MHC Multimer

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1068 APC-DRB1*02:01/Human HLA-A (VGSDWRFLRGYHQYA) MHC Tetramer FCM
MHC-LC1867 BV421-DRB1*01:01/Human HLA-A (GSDARFLRGYHLYA) MHC Tetramer FCM
MHC-LC4476 PE-B*15:01/Human HLA-A (VGYVDDTQF) MHC Tetramer FCM
MHC-LC4477 PE-B*58:01/Human HLA-A (VGYVDDTQF) MHC Tetramer FCM
MHC-LC4492 PE-H2-Kd/Human HLA-A (RYLENGKETL) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1617 Rabbit Anti-HLA-A Recombinant Antibody (clone DS1617AB) FC, ICC, IF, IHC-Fr, IHC-P, IP, WB Rabbit IgG

Customer Reviews and Q&As

Submit a review or a question
Thare are currently no Customer reviews or questions for MHC-LC594. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

Send Inquiry

© 2022 Creative BioLabs. All Rights Reserved
  • 0
  • 0

Cart