EMCH (N-ε-maleimidocaproic acid hydrazide) (CAT#: Glyco-018CL)

EMCH is a mid-length, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Specific Inquiry
  • Datasheet
  • MSDS
  • COA


  • Product Size
  • 50 mg
  • Spacer
  • Mid-Length
  • Solubility
  • Water
  • Labeling Method
  • Chemical Labeling
  • Crosslinker Type
  • Heterobifunctional
  • Specifications
  • We manufacture EMCH to the highest specifications to produce the most specific bioconjugates, ensure the integrity of your data and to provide you with the highest degree of consistency. Each lot of EMCH is tested to meet the following minimum specifications:

    • NMR purity:>90%
    • Melting point: 99-110°C
    • Identity: IR scan shows only peaks characteristic of the structure and functional groups of EMCH
  • Contents & storage
  • Store desiccated at 4°C. Shipped at ambient temperature.


  • Description
  • 3,3'-N-[ε-Maleimidocaproic acid] hydrazide, trifluoroacetic acid salt (EMCH) is a water-soluble, heterobifunctional, membrane permeable crosslinker. It contains a sulfhydryl reactive maleimide group and carbonyl reactive hydrazide group at each end of a 6-carbon spacer arm. Maleimides react with sulfhydryls at pH 6.5-7.5 to form stable thiol ether bonds, along with release of the maleimide leaving group. Proteins with cysteine residues not involved in disulfide bond formation are targets for maleimide reactive groups. Carbonyl groups, whilst not found naturally on proteins can be formed by ring sugar reduction to form aldehydes which react with hydrazides at pH5.5-7.5.
  • Properties


Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for ""

Customer Reviews and Q&As

Submit a review or a question
Thare are currently no Customer reviews or questions for Glyco-018CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
REImmunohistology - Resin Sections
IRMAImmunoradiometric Assay
SHIn situ hybridization
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
RIRadial Immunodiffusion
SPRSurface Plasmon Resonance
WBWestern Blot

Send Inquiry

© 2022 Creative BioLabs. All Rights Reserved
  • 0
  • 0