Enfuvirtide (CAT#: TP-099CL)
Enfuvirtide is a 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. It is an N-terminal acetylated, C-terminal amide. As an HIV fusion inhibitor, it is the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
Specifications
- Classify
- Protein therapeutics that interfere with a molecule or organism: Infectious diseases
- Therapeutic
- Enfuvirtide
- Trade Name
- Fuzeon
- Function
- 36 amino-acid peptide that inhibits Hiv entry into host cells by binding to the Hiv envelope protein gp120/gp41
- Examples of clinical use
- Adults and children (at least 6 years old) with advanced Hiv infection
References
- Synonyms
- Envelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41]
- UniProt
- Q70626
- Genbank
- U12055
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L012R | anti-env immunotoxin 907 (IgG)-RTA | Cytotoxicity assay, Functional assay |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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