Enfuvirtide (CAT#: TP-099CL)
Enfuvirtide is a 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. It is an N-terminal acetylated, C-terminal amide. As an HIV fusion inhibitor, it is the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
Specifications
- Classify
- Protein therapeutics that interfere with a molecule or organism: Infectious diseases
- Therapeutic
- Enfuvirtide
- Trade Name
- Fuzeon
- Function
- 36 amino-acid peptide that inhibits Hiv entry into host cells by binding to the Hiv envelope protein gp120/gp41
- Examples of clinical use
- Adults and children (at least 6 years old) with advanced Hiv infection
References
- Synonyms
- Envelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41]
- UniProt
- Q70626
- Genbank
- U12055
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "env"
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L012R | anti-env immunotoxin 907 (IgG)-RTA | Cytotoxicity assay, Functional assay |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody scFv Fragment | Neut, FuncS | scFv |
| PSBL-435 | Recombinant Human Anti-DENV Env Antibody scFv Fragment (EDE1 A11) | Neut | scFv |
| PSBL-436 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-436) | Neut | Human scFv |
| PSBL-572 | Recombinant Human Anti-HPV Env Antibody scFv Fragment (mAb-94) | WB, IF, FuncS | scFv |
| PFBC-210 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (3BNC60) | ELISA, Neut | Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody Fab Fragment | Neut, FuncS | Fab |
| PFBL-572 | Recombinant Human Anti-HPV Env Antibody Fab Fragment (mAb-94) | WB, IF, FuncS | Fab |
| PSBZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT 135) | ELISA, Neut | scFv |
| PSBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (45-46M2) | ELISA, Neut | scFv |
| PSBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT121) | Neut, ELISA | scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-020 | Recombinant Anti-HIV ENV VHH Single Domain Antibody (JM4) | ELISA, SPR, Neut, FuncS | Llama VHH |
| PNBL-021 | Recombinant Anti-HIV-1 ENV VHH Single Domain Antibody (2H10) | Neut, WB, ELISA, FuncS | Llama VHH |
| PNBL-059 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody (D7) | ELISA, Inhib | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-141 | Human Anti-ENV Recombinant Antibody (clone 2F5) | Neut | Human IgG |
| PABZ-160 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT123) | FACS, Neut | IgG |
| PABZ-161 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT122) | FACS, Neut | IgG |
| PABZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT 135) | ELISA, Neut | IgG |
| PABZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody (45-46M2) | ELISA, Neut | IgG |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF410 | A*02:01/HIV Env (SLLNATAIAV) MHC Pentamer | FCM | |
| MHC-YF411 | A*29:02/HIV Env (SFDPIPIHY) MHC Pentamer | FCM | |
| MHC-YF412 | A*29:02/HIV Env (SFNCRGEFFY) MHC Pentamer | FCM | |
| MHC-YF413 | B*08:01/HIV Env (YLKDQQLL) MHC Pentamer | FCM | |
| MHC-YF497 | H-2Dd/HIV IIIB gp120 (RGPGRAFVTI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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